New neurons are constantly being generated in the postnatal subventricular zone. They
have to migrate long distances via the rostral migratory stream (RMS) to reach their final …

Targeted genome editing enables the creation of bona fide cellular models for biological
research and may be applied to human cell-based therapies. Therefore, broadly applicable and …

Microglia surrounds the amyloid plaques that form in the brains of patients with Alzheimer’s
disease (AD), but their role is controversial. Under inflammatory conditions, these cells can …

Background Experimental autoimmune encephalomyelitis (EAE) is a model of inflammatory
demyelinating diseases mediated by different types of leukocytes. How these cells …

The fragile X autosomal homolog 1 (Fxr1) is regulated by lithium and has been GWAS‐associated
with schizophrenia and insomnia. Homeostatic regulation of synaptic strength is …

Genome editing using designer nucleases has revolutionized molecular biology by allowing
DNA to be inserted, deleted or replaced in the genome of several model organisms. This …

Targeted genome editing using engineered nucleases facilitates the creation of bona fide
cellular models for biological research and may be applied to human cell-based therapies. …

Cryopreservation of mobilized apheresis products could prove to be very important in the
manufacture of scalable and more globally accessible cell-based gene therapies. However, it …

Microglia surround the amyloid plaques that form in the brains of patients with Alzheimer's
disease (AD), but their role is controversial. Under inflammatory conditions, these cells can …

La maison royale des Arsacides ou Parthes a fait son apparition dans l’arène historique
vers l’an 250 av. J.-C., en se séparant de l’État séleucide hellénistique, formé à la suite des …