Astrocytes control the development of the migration-promoting vasculature scaffold in the postnatal brain via VEGF signaling
L Bozoyan, J Khlghatyan… - Journal of …, 2012 - Soc Neuroscience
New neurons are constantly being generated in the postnatal subventricular zone. They
have to migrate long distances via the rostral migratory stream (RMS) to reach their final …
have to migrate long distances via the rostral migratory stream (RMS) to reach their final …
Marker-free coselection for CRISPR-driven genome editing in human cells
D Agudelo, A Duringer, L Bozoyan, CC Huard… - Nature …, 2017 - nature.com
Targeted genome editing enables the creation of bona fide cellular models for biological
research and may be applied to human cell-based therapies. Therefore, broadly applicable and …
research and may be applied to human cell-based therapies. Therefore, broadly applicable and …
GPR84 deficiency reduces microgliosis, but accelerates dendritic degeneration and cognitive decline in a mouse model of Alzheimer's disease
J Audoy-Rémus, L Bozoyan, A Dumas, M Filali… - Brain, behavior, and …, 2015 - Elsevier
Microglia surrounds the amyloid plaques that form in the brains of patients with Alzheimer’s
disease (AD), but their role is controversial. Under inflammatory conditions, these cells can …
disease (AD), but their role is controversial. Under inflammatory conditions, these cells can …
[HTML][HTML] Interleukin-36γ is expressed by neutrophils and can activate microglia, but has no role in experimental autoimmune encephalomyelitis
L Bozoyan, A Dumas, A Patenaude… - Journal of …, 2015 - Springer
Background Experimental autoimmune encephalomyelitis (EAE) is a model of inflammatory
demyelinating diseases mediated by different types of leukocytes. How these cells …
demyelinating diseases mediated by different types of leukocytes. How these cells …
Fxr1 regulates sleep and synaptic homeostasis
J Khlghatyan, A Evstratova, L Bozoyan… - The EMBO …, 2020 - embopress.org
The fragile X autosomal homolog 1 (Fxr1) is regulated by lithium and has been GWAS‐associated
with schizophrenia and insomnia. Homeostatic regulation of synaptic strength is …
with schizophrenia and insomnia. Homeostatic regulation of synaptic strength is …
A marker-free co-selection strategy for high efficiency homology-driven and NHEJ-based gene editing in human cells
Genome editing using designer nucleases has revolutionized molecular biology by allowing
DNA to be inserted, deleted or replaced in the genome of several model organisms. This …
DNA to be inserted, deleted or replaced in the genome of several model organisms. This …
A marker-free co-selection strategy for high efficiency human genome engineering
D Agudelo, L Bozoyan, A Duringer, CC Huard, S Carter… - bioRxiv, 2017 - biorxiv.org
Targeted genome editing using engineered nucleases facilitates the creation of bona fide
cellular models for biological research and may be applied to human cell-based therapies. …
cellular models for biological research and may be applied to human cell-based therapies. …
Quality implications of cryopreservation: Building a small-scale model to determine the shelf-life of cryopreserved blood products for drug product manufacturing
…, L Bozoyan, C Jones, F John Pierciey, L Chan - 2022 - dc.engconfintl.org
Cryopreservation of mobilized apheresis products could prove to be very important in the
manufacture of scalable and more globally accessible cell-based gene therapies. However, it …
manufacture of scalable and more globally accessible cell-based gene therapies. However, it …
GPR84 deficiency reduces microgliosis, but accelerates dendritic degeneration and cognitive decline in a mouse model of Alzheimer's disease
L Bozoyan, J Audoy-rémus, A Dumas… - Journal of …, 2014 - jni-journal.com
Microglia surround the amyloid plaques that form in the brains of patients with Alzheimer's
disease (AD), but their role is controversial. Under inflammatory conditions, these cells can …
disease (AD), but their role is controversial. Under inflammatory conditions, these cells can …
[PDF][PDF] L'interprétation de la dynastie Arsacide dans l'historiographie Médiévale Arménienne
A Bozoyan - Բանբեր Հայագիտության= Вестник Арменоведения …, 2020 - academia.edu
La maison royale des Arsacides ou Parthes a fait son apparition dans l’arène historique
vers l’an 250 av. J.-C., en se séparant de l’État séleucide hellénistique, formé à la suite des …
vers l’an 250 av. J.-C., en se séparant de l’État séleucide hellénistique, formé à la suite des …