[HTML][HTML] Antimicrobial peptides: multifunctional drugs for different applications

LO Brandenburg, J Merres, LJ Albrecht, D Varoga… - Polymers, 2012 - mdpi.com
Antimicrobial peptides (APs) are an important part of the innate immune system in epithelial
and non-epithelial surfaces. So far, many different antimicrobial peptides from various …

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions

…, L Brandenburg, G Mbamalu, M Tucholska, L Spatt… - Nature cell …, 2020 - nature.com
Rho GTPases are central regulators of the cytoskeleton and, in humans, are controlled by
145 multidomain guanine nucleotide exchange factors (RhoGEFs) and GTPase-activating …

Role of oxidative stress in rheumatoid arthritis: insights from the Nrf2-knockout mice

…, A Fragoulis, A Gurzynski, LO Brandenburg… - Annals of the …, 2011 - ard.bmj.com
Objectives Increasing evidence suggests that oxidative stress may play a key role in joint
destruction due to rheumatoid arthritis (RA). The aim of this study was to elucidate the role of …

Human neuromelanin induces neuroinflammation and neurodegeneration in the rat substantia nigra: implications for Parkinson's disease

…, H Wilms, S Geick, JH Claasen, LO Brandenburg… - Acta …, 2008 - Springer
Parkinson's disease (PD) is a common neurodegenerative disorder characterized by a
selective loss of dopaminergic neurons in the substantia nigra (SN). It has been suggested that …

Capacity of the Gaussian channel with memory: The multivariate case

LH Brandenburg, AD Wyner - Bell System Technical Journal, 1974 - Wiley Online Library
… We show that if has a bounded inverse in L. Now det F(6) is a scalar function consisting
of a sum of products of functions each possessing an absolutely convergent Fourier series.‘ …

Receptor endocytosis counteracts the development of opioid tolerance

…, A Widera, K Bartzsch, S Schulz, LO Brandenburg… - Molecular …, 2005 - ASPET
… Cells were seeded at a density of 2 × 10 5 per well and grown onto poly-l-lysine-treated
24-well plates overnight. After washing, cells were preincubated with 1 μg of affinity-purified …

Role of receptor internalization in the agonist‐induced desensitization of cannabinoid type 1 receptors

…, A Goschke, R Stumm, LO Brandenburg… - Journal of …, 2008 - Wiley Online Library
… to 10 μmol/L AEA, 10 μmol/L 2-arachidonoyl glycerol (2-AG) or 1 μmol/L CP 55940 (CP) for
… 10 μmol/L AEA, 10 μmol/L 2-AG or 1 μmol/L CP in the presence of 50 μmol/L monensin (Mon…

Sulforaphane suppresses LPS-induced inflammation in primary rat microglia

LO Brandenburg, M Kipp, R Lucius, T Pufe… - Inflammation …, 2010 - Springer
Objective and design The aim of this study was to investigate the signal transduction
pathways involved in sulforaphane (SF) mediated inhibition of the inflammatory response to …

[HTML][HTML] Nrf2 induces interleukin-6 (IL-6) expression via an antioxidant response element within the IL-6 promoter

…, ME Götz, M Tohidnezhad, LO Brandenburg… - Journal of Biological …, 2011 - ASBMB
IL-6 gene expression is controlled by a promoter region containing multiple regulatory
elements such as NF-κB, NF-IL6, CRE, GRE, and TRE. In this study, we demonstrated that TRE, …

Kavalactones protect neural cells against amyloid β peptide-induced neurotoxicity via extracellular signal-regulated kinase 1/2-dependent nuclear factor erythroid 2 …

…, T Herdegen, D Varoga, LO Brandenburg… - Molecular …, 2008 - ASPET
One hallmark of Alzheimer's disease is the accumulation of amyloid β-peptide (AP), which
can initiate a cascade of oxidative events that may result in neuronal death. Because nuclear …