User profiles for L. Bry

Lynn Bry

Director, Massachusetts Host-Microbiome Center, Associate Professor of Pathology
Verified email at madsci.org
Cited by 12911

Effects of hemoglobin variants and chemically modified derivatives on assays for glycohemoglobin

L Bry, PC Chen, DB Sacks - Clinical chemistry, 2001 - academic.oup.com
Background: Glycohemoglobin (gHb), measured as hemoglobin (Hb) A 1c or as total gHb,
provides a common means for assessing long-term glycemic control in individuals with …

Host–microbial symbiosis in the mammalian intestine: exploring an internal ecosystem

LV Hooper, L Bry, PG Falk, JI Gordon - Bioessays, 1998 - Wiley Online Library
… Conventionalization of germfree mice also results in transcriptional activation of a host
GDP-L-fucose:- D-galactoside 2--L-fucosyltransferase gene in the ileum.Remarkably, a single …

A model of host-microbial interactions in an open mammalian ecosystem

L Bry, PG Falk, T Midtvedt, JI Gordon - Science, 1996 - science.org
… We examined whether the bacteria's ability to metabolize L-… of Tn4351 rendering it unllable
to use L-fucose or D-arabinose … organism's abilitv to take up 3H]L-fucose or to colonize and …

[HTML][HTML] Alterations of the human gut microbiome in multiple sclerosis

…, PL De Jager, FJ Quintana, GK Gerber, L Bry… - Nature …, 2016 - nature.com
The gut microbiome plays an important role in immune function and has been implicated in
several autoimmune disorders. Here we use 16S rRNA sequencing to investigate the gut …

Epithelial cell growth and differentiation. III. Promoting diversity in the intestine: conversations between the microflora, epithelium, and diffuse GALT

…, MS McNevin, M Wong, L Bry - American Journal of …, 1997 - journals.physiology.org
l The complexity of the gut microflora in mice raised under conventional … l The ability of
components … Thy-l expression and the cytolytic activity of intraepithelial lymphocytes are induced …

[PDF][PDF] Enterobacteriaceae act in concert with the gut microbiota to induce spontaneous and maternally transmitted colitis

…, A DuBois, ML Delaney, S Punit, M Karlsson, L Bry… - Cell host & …, 2010 - cell.com
Disruption of homeostasis between the host immune system and the intestinal microbiota
leads to inflammatory bowel disease (IBD). Whether IBD is instigated by individual species or …

[PDF][PDF] The host shapes the gut microbiota via fecal microRNA

…, AP Da Cunha, RM Rezende, R Cialic, Z Wei, L Bry… - Cell host & …, 2016 - cell.com
The host gut microbiota varies across species and individuals but is relatively stable over
time within an individual. How the host selectively shapes the microbiota is largely unclear. …

Mechanism of CD1d-restricted natural killer T cell activation during microbial infection

M Brigl, L Bry, SC Kent, JE Gumperz, MB Brenner - Nature immunology, 2003 - nature.com
… for 3 d in granulocyte-monocyte colony-stimulating factor (300 U/ml; Sargramostim; Immunex)
and IL-4 (200 U/ml; PeproTech) in complete RPMI medium (RPMI supplemented with L-…

[PDF][PDF] Interactions between gut microbiota, host genetics and diet modulate the predisposition to obesity and metabolic syndrome

…, S Fujisaka, S Vienberg, S Softic, L Deng, L Bry… - Cell metabolism, 2015 - cell.com
… negatively correlated with OTU 323257 (L. gasseri). Consistent with the group-wise analysis
across all mouse strains on both CD and HFD (Figure 6B), L. gasseri was strongly positively …

Thymus-derived regulatory T cells contribute to tolerance to commensal microbiota

…, TL Denning, L Bry, P Kraj, P Kisielow, L Ignatowicz - Nature, 2013 - nature.com
Peripheral mechanisms preventing autoimmunity and maintaining tolerance to commensal
microbiota involve CD4 + Foxp3 + regulatory T (T reg ) cells 1 , 2 generated in the thymus or …