A complex role for FGF-2 in self-renewal, survival, and adhesion of human embryonic stem cells
L Eiselleova, K Matulka, V Kriz, M Kunova… - Stem …, 2009 - academic.oup.com
The transcription program that is responsible for the pluripotency of human ESCs (hESCs)
is believed to be comaintained by exogenous fibroblast growth factor-2 (FGF-2), which …
is believed to be comaintained by exogenous fibroblast growth factor-2 (FGF-2), which …
[PDF][PDF] Comparative study of mouse and human feeder cells for human embryonic stem cells
L Eiselleova, I Peterkova, J Neradil… - International Journal of …, 2008 - academia.edu
Various types of feeder cells have been adopted for the culture of human embryonic stem
cells (hESCs) to improve their attachment and provide them with stemness-supporting factors. …
cells (hESCs) to improve their attachment and provide them with stemness-supporting factors. …
Computer‐assisted engineering of hyperstable fibroblast growth factor 2
…, P Vanacek, L Balek, L Eiselleova… - Biotechnology and …, 2018 - Wiley Online Library
Fibroblast growth factors (FGFs) serve numerous regulatory functions in complex organisms,
and their corresponding therapeutic potential is of growing interest to academics and …
and their corresponding therapeutic potential is of growing interest to academics and …
FiloGen: a model-based generator of synthetic 3-D time-lapse sequences of single motile cells with growing and branching filopodia
…, K Morgaenko, L Eiselleová, L Tesařová… - … on Medical Imaging, 2018 - ieeexplore.ieee.org
The existence of diverse image datasets accompanied by reference annotations is a crucial
prerequisite for an objective benchmarking of bioimage analysis methods. Nevertheless, …
prerequisite for an objective benchmarking of bioimage analysis methods. Nevertheless, …
Adaptation to robust monolayer expansion produces human pluripotent stem cells with improved viability
M Kunova, K Matulka, L Eiselleova… - Stem Cells …, 2013 - academic.oup.com
The generation of human pluripotent stem cells (hPSCs) of sufficient quantity and quality
remains a major challenge for biomedical application. Here we present an efficient feeder-free, …
remains a major challenge for biomedical application. Here we present an efficient feeder-free, …
Decrease in abundance of apurinic/apyrimidinic endonuclease causes failure of base excision repair in culture-adapted human embryonic stem cells
…, L Bálek, R Hejnová, Z Dobšáková, L Eiselleová… - Stem Cells, 2013 - academic.oup.com
The inevitable accumulation of chromosomal abnormalities in human embryonic stem cells (hESCs)
during in vitro expansion represents a considerable obstacle for cell replacement …
during in vitro expansion represents a considerable obstacle for cell replacement …
Development of humanized culture medium with plant-derived serum replacement for human pluripotent stem cells
M Kunova, K Matulka, L Eiselleova, P Trckova… - Reproductive …, 2010 - Elsevier
For human embryonic stem cells (ESC) to be used in cell replacement therapies, they must
be grown under good manufacturing conditions in a chemically defined medium that lacks …
be grown under good manufacturing conditions in a chemically defined medium that lacks …
[HTML][HTML] The Role of RNA Polymerase II Contiguity and Long-Range Interactions in the Regulation of Gene Expression in Human Pluripotent Stem Cells
L Eiselleova, V Lukjanov, S Farkas, D Svoboda… - Stem Cells …, 2019 - hindawi.com
The eukaryotic nucleus is a highly complex structure that carries out multiple functions
primarily needed for gene expression, and among them, transcription seems to be the most …
primarily needed for gene expression, and among them, transcription seems to be the most …
Development of humanized culture medium with plant-derived serum replacement for human pluripotent stem cells
M Bosáková, K Matulka, L Eiselleová, P Trčková… - 2010 - med.muni.cz
For human embryonic stem cells (ESC) to be used in cell replacement therapies, they must
be grown under good manufacturing conditions in a chemically defined medium that lacks …
be grown under good manufacturing conditions in a chemically defined medium that lacks …