The RNA exosome is a conserved degradation machinery, which obtains full activity only
when associated with cofactors. The most prominent activator of the yeast nuclear exosome is …

… RPMI 1640 medium at 37C, 5% CO 2 in a humidified incubator with normal l‐lysine (Lys0)
and l‐arginine (Arg0) or isotope‐labelled l‐lysine 2 H 4 (Lys4) or 13 C 6 15 N 2 (Lys8) and …

To further integrate mass spectrometry (MS)-based proteomics into biomedical research and
especially into clinical settings, high throughput and robustness are essential requirements. …

… Light condition medium was supplemented with l-lysine 2HCl (Lys0) l-arginine HCl (Arg0).
The concentrations of supplemented amino acids used were 50 mg/L. The cells were …

For rational design of therapeutic vaccines, detailed knowledge about target epitopes that are
endogenously processed and truly presented on infected or transformed cells is essential. …

… bacteriochlorophyll (BChl) a concentration of 41 µg l −1 at 12 m, whereas the highest
concentration of BChl e from the brown GSB was 231 µg l −1 at 12.25 m just below the PSB …

The high peptide sequencing speed provided by modern hybrid tandem mass spectrometers
enables the utilization of fast liquid chromatographic (LC) separation techniques. We …

C hlorobaculum (C ba.) tepidum is a green sulfur bacterium that oxidizes sulfide, elemental
sulfur, and thiosulfate for photosynthetic growth. To gain insight into the sulfur metabolism, …

The molecular mechanisms underlying how cells sense, respond, and adapt to alterations
in nutrient availability have been studied extensively during the past years. While most of …

Proteomic identifications hinge on the measurement of both parent and fragment masses and
matching these to amino acid sequences via database search engines. The correctness of …