Background Full-thickness chondral defects and early osteoarthritis continue to present major
challenges for the patient and the orthopaedic surgeon as a result of the limited healing …

… Citation 57 Unexpectedly, it was found that the genomic sequences were exchanged
with endogenous prophages present in the L. lactis host used in these experiments. …

The application of stem cells in regenerative and reparative therapies is emerging in surgery.
Published information can lead to an over simplified view of stem cells with respect to their …

This article investigates the probable causes of compulsive buying, proposes a conceptual
framework to explain the phenomenon, and develops an appropriate measuring scale. The …

… For example, McCarrel and Fortier 14 showed that leukocytes in a PRP preparation had a
negative correlation with matrix synthesis and a positive correlation with matrix catabolism in …

Platelet rich plasma (PRP) has recently been investigated for use in tissue regeneration
studies that seek to utilize the numerous growth factors released from platelet α‐granules. This …

… , one of which is clearly proinflammatory and contains numerous cytokines including cathepsin
B, L, and S; MMP-2, 3, 9, 13; and … Drs Fortier and Cole are paid consultants for Arthrex. …

Background: The purpose of this study was to compare the outcomes of treatment with bone
marrow aspirate concentrate, a simple, one-step, autogenous, and arthroscopically …

Abstract Analysis of modern and historical observations demonstrates that the temperature
of the intermediate-depth (150–900 m) Atlantic water (AW) of the Arctic Ocean has increased …

… Briefly, 100 l of synovial fluid were incubated with 900 l of acid-ethanol solution (12.5%
2N HCl/87.5% v/v) to dissociate IGF-I from IGF-binding proteins. The resulting solution was …