Proteotyping: Proteomic characterization, classification and identification of microorganisms–A prospectus

R Karlsson, L Gonzales-Siles, F Boulund… - Systematic and applied …, 2015 - Elsevier
Modern microbial systematics requires a range of methodologies for the comprehensive
characterization, classification and identification of microorganisms. While whole-genome …

The different ecological niches of enterotoxigenic Escherichia coli

L GonzalesSiles, Å Sjöling - Environmental microbiology, 2016 - Wiley Online Library
… Additionally, upregulation of the DsbA protein and the Sec-dependent transport system was
found under alkaline conditions (L. Gonzales-Siles et al., submitted). DsbA is involved in the …

[HTML][HTML] Typing and characterization of bacteria using bottom-up tandem mass spectrometry proteomics

F Boulund, R Karlsson, L Gonzales-Siles… - Molecular & Cellular …, 2017 - ASBMB
Methods for rapid and reliable microbial identification are essential in modern healthcare.
The ability to detect and correctly identify pathogenic species and their resistance phenotype …

[HTML][HTML] Diarrheal bacterial pathogens and multi-resistant enterobacteria in the Choqueyapu River in La Paz, Bolivia

J Guzman-Otazo, L Gonzales-Siles, V Poma… - PLoS …, 2019 - journals.plos.org
Water borne diarrheal pathogens might accumulate in river water and cause contamination
of drinking and irrigation water. The La Paz River basin, including the Choqueyapu River, …

[HTML][HTML] High rate of antibiotic resistance among pneumococci carried by healthy children in the eastern part of the Democratic Republic of the Congo

…, E Samuelsson, S Geravandi, L Gonzales-Siles… - BMC pediatrics, 2018 - Springer
Background Pneumococcal conjugate vaccines have been introduced in the infant immunisation
programmes in many countries to reduce the rate of fatal pneumococcal infections. In …

[HTML][HTML] Proteotyping bacteria: Characterization, differentiation and identification of pneumococcus and other species within the Mitis Group of the genus …

R Karlsson, L Gonzales-Siles, M Gomila, A Busquets… - PloS one, 2018 - journals.plos.org
A range of methodologies may be used for analyzing bacteria, depending on the purpose
and the level of resolution needed. The capability for recognition of species distinctions within …

[HTML][HTML] Carriage of penicillin-non-susceptible pneumococci among children in northern Tanzania in the 13-valent pneumococcal vaccine era

…, BM Nyombi, D Mosha, L Gonzales-Siles… - International Journal of …, 2019 - Elsevier
Objectives To determine the antibiotic susceptibility and serotype distribution of colonizing
Streptococcus pneumoniae in Tanzanian children. Serial cross-sectional surveys were …

[HTML][HTML] A pangenome approach for discerning species-unique gene markers for identifications of Streptococcus pneumoniae and Streptococcus pseudopneumoniae

L Gonzales-Siles, R Karlsson, P Schmidt… - Frontiers in cellular …, 2020 - frontiersin.org
Correct identifications of isolates and strains of the Mitis-Group of the genus Streptococcus
are particularly difficult, due to high genetic similarity, resulting from horizontal gene transfer …

[HTML][HTML] Discovery of species-unique peptide biomarkers of bacterial pathogens by tandem mass spectrometry-based proteotyping

…, HE Jakobsson, L Gonzales-Siles… - Molecular & Cellular …, 2020 - ASBMB
Mass spectrometry (MS) and proteomics offer comprehensive characterization and
identification of microorganisms and discovery of protein biomarkers that are applicable for …

Identification and capsular serotype sequetyping of Streptococcus pneumoniae strains

L Gonzales-Siles, F Salvà-Serra… - Journal of Medical …, 2019 - microbiologyresearch.org
Purpose. Correct serotype identification of Streptococcus pneumoniae (pneumococcus) is
important for monitoring disease epidemiology and assessing the impacts of pneumococcal …