[PDF][PDF] Condensation of Ded1p promotes a translational switch from housekeeping to stress protein production

…, AW Fritsch, M Mittasch, A Domingues, L Hersemann… - Cell, 2020 - cell.com
Cells sense elevated temperatures and mount an adaptive heat shock response that involves
changes in gene expression, but the underlying mechanisms, particularly on the level of …

[HTML][HTML] A 3D system to model human pancreas development and its reference single-cell transcriptome atlas identify signaling pathways required for progenitor …

…, A Nakamura, M Leuschner, L Hersemann… - Nature …, 2021 - nature.com
Human organogenesis remains relatively unexplored for ethical and practical reasons. Here,
we report the establishment of a single-cell transcriptome atlas of the human fetal pancreas …

[HTML][HTML] CD-CODE: crowdsourcing condensate database and encyclopedia

…, C Landerer, R Ghosh, HK Moon, L Hersemann… - Nature …, 2023 - nature.com
The discovery of biomolecular condensates transformed our understanding of intracellular
compartmentalization of molecules. To integrate interdisciplinary scientific knowledge about …

A novel population of Hopx-dependent basal radial glial cells in the developing mouse neocortex

S Vaid, JG Camp, L Hersemann… - …, 2018 - journals.biologists.com
A specific subpopulation of neural progenitor cells, the basal radial glial cells (bRGCs) of
the outer subventricular zone (OSVZ), are thought to have a key role in the evolutionary …

The noncanonical type III secretion system of Xanthomonas translucens pv. graminis is essential for forage grass infection

F Wichmann, FJ Vorhölter, L Hersemann… - Molecular plant …, 2013 - Wiley Online Library
… (b) Colonization of L. multiflorum by Xtg29 and the Xtg29 strains deficient in T3SS genes.
Bacterial population densities were determined for leaves of three or four different plants of …

Complete Genome Sequence of the Barley Pathogen Xanthomonas translucens pv. translucens DSM 18974T (ATCC 19319T)

…, D Wibberg, C Spröer, L Hersemann… - Genome …, 2016 - Am Soc Microbiol
We report here the complete 4.7-Mb genome sequence of Xanthomonas translucens pv.
translucens DSM 18974 T , which causes black chaff disease on barley (Hordeum vulgare). …

[HTML][HTML] Comparative genomics of host adaptive traits in Xanthomonas translucens pv. graminis

L Hersemann, D Wibberg, J Blom, A Goesmann… - BMC genomics, 2017 - Springer
… Size of dots indicates the number of replicates allocated to a particular score, each represented
by one clonal replicate of the L. multiflorum genotype LmK-01. Orange bars indicate the …

[PDF][PDF] Integrating single-cell imaging and RNA sequencing datasets links differentiation and morphogenetic dynamics of human pancreatic endocrine progenitors

BS Beydag-Tasöz, JV D'Costa, L Hersemann… - Developmental Cell, 2023 - cell.com
Basic helix-loop-helix genes, particularly proneural genes, are well-described triggers of cell
differentiation, yet information on their dynamics is limited, notably in human development. …

The novel Rab5 effector FERRY links early endosomes with the translation machinery

…, C Landerer, J Davila Gallesio, L Hersemann… - BioRxiv, 2021 - biorxiv.org
Local translation is vital to polarized cells such as neurons and requires a precise and robust
distribution of different mRNAs and the translation machinery across the entire cell. The …

[HTML][HTML] Molecular investigation of isolates from a multistate polymicrobial outbreak associated with contaminated total parenteral nutrition in Brazil

…, AF Martins, AL Barth, A Mazzetti, L Hersemann… - BMC infectious …, 2018 - Springer
Background Between November 2013 and June 2014, 56 cases of bacteremia (15 deaths)
associated with the use of Total Parenteral Nutrition (TPN) and/or calcium gluconate (CG) …