User profiles for L. Hollingsworth

Louis "Bobby" Hollingsworth

Postdoctoral Fellow, Harvard Medical School
Verified email at vt.edu
Cited by 1069

Mechanism and regulation of gasdermin-mediated cell death

S Xia, LR Hollingsworth, H Wu - Cold Spring Harbor …, 2020 - cshperspectives.cshlp.org
The innate immune system senses and responds to pathogens and endogenous damage
through supramolecular protein complexes known as inflammasomes. Cytosolic …

FDA-approved disulfiram inhibits pyroptosis by blocking gasdermin D pore formation

…, J Wang, LR Hollingsworth, VG Magupalli, L Zhao… - Nature …, 2020 - nature.com
Cytosolic sensing of pathogens and damage by myeloid and barrier epithelial cells
assembles large complexes called inflammasomes, which activate inflammatory caspases to …

Molecular cloning of a ligand for the flt3flk-2 tyrosine kinase receptor: A proliferative factor for primitive hematopoietic cells

…, P de Vries, K Brasel, B Gliniak, LT Hollingsworth… - Cell, 1993 - cell.com
… Free and cell-bound ll-labeled antibody were quantlffed on a Packard Autogamma
Counter. Affinity and other binding calculations (Scatchard, 1949) were generated on RS/…

Promoting same-race adoption for children of color

LD Hollingsworth - Social Work, 1998 - academic.oup.com
Opponents of policies that protect same-race adoption assert that children of color are
languishing in out-of-home care because they are being restricted from entering transracial …

[HTML][HTML] Dose-dependent blockade to cardiomyocyte hypertrophy by histone deacetylase inhibitors

…, TA McKinsey, M Dreitz, LM Hollingsworth… - Journal of Biological …, 2003 - ASBMB
Postnatal cardiac myocytes respond to stress signals by hypertrophic growth and activation
of a fetal gene program. Recently, we showed that class II histone deacetylases (HDACs) …

Lectin/glycan interactions play a role in recognition in a coral/dinoflagellate symbiosis

EM Wood‐Charlson, LL Hollingsworth… - Cellular …, 2006 - Wiley Online Library
Recognition is an important stage in the establishment of highly specific mutualistic associations.
Yet, for the majority of symbioses, very few of the mechanisms involved in recognition …

DPP9 sequesters the C terminus of NLRP1 to repress inflammasome activation

LR Hollingsworth, H Sharif, AR Griswold, P Fontana… - Nature, 2021 - nature.com
Nucleotide-binding domain and leucine-rich repeat pyrin-domain containing protein 1 (NLRP1)
is an inflammasome sensor that mediates the activation of caspase-1 to induce cytokine …

Effect of transracial/transethnic adoption on children's racial and ethnic identity and self-esteem: A meta-analytic review

LD Hollingsworth - Marriage & Family Review, 1997 - Taylor & Francis
This paper reports the results of a meta-analytic review of comparative studies of racial identity
and self-esteem in transra-cially/transethnically-adopted, inracially-adopted/same ethnic …

[HTML][HTML] Role of ARP2/3 complex-driven actin polymerization in RSV infection

A Paluck, J Osan, L Hollingsworth, SN Talukdar… - Pathogens, 2021 - mdpi.com
Respiratory syncytial virus (RSV) is the leading viral agent causing bronchiolitis and
pneumonia in children under five years old worldwide. The RSV infection cycle starts with …

Effects of photovoice: Civic engagement among older youth in urban communities

…, L Smith, P Miller, LA Hollingsworth… - Journal of community …, 2009 - Taylor & Francis
Youth civic engagement is critical to many community empowerment initiatives. Photovoice
is a popular empowerment technique for disenfranchised groups, including youth. The …