[HTML][HTML] Glycosidase activated prodrugs for targeted cancer therapy

H Martin, LR Lázaro, T Gunnlaugsson… - Chemical Society …, 2022 - pubs.rsc.org
In this review glycosidase activated prodrugs that target cancer cells are discussed.
Glycosylated prodrugs undergo enzymatic bioconversion, cleaving the prodrug to release the …

Distinct subcortical volume alterations in pediatric and adult OCD: a worldwide meta-and mega-analysis

…, K Koch, JS Kwon, L Lazaro… - American Journal of …, 2017 - Am Psychiatric Assoc
Objective: Structural brain imaging studies in obsessive-compulsive disorder (OCD) have
produced inconsistent findings. This may be partially due to limited statistical power from …

Cortical thickness across the lifespan: Data from 17,075 healthy individuals aged 3–90 years

…, J Kuntsi, J Lagopoulos, L Lázaro… - Human brain …, 2022 - Wiley Online Library
Delineating the association of age and cortical thickness in healthy individuals is critical
given the association of cortical thickness with cognition and behavior. Previous research has …

Diagnostic biomarkers for obsessive-compulsive disorder: A reasonable quest or ignis fatuus?

…, E Vieta, C Soriano-Mas, L Lázaro… - Neuroscience & …, 2020 - Elsevier
Obsessive-compulsive disorder (OCD) has been associated with a wide range of biological
and neurocognitive findings, which could assist in the search for biomarkers. We conducted …

Cortical abnormalities associated with pediatric and adult obsessive-compulsive disorder: findings from the ENIGMA Obsessive-Compulsive Disorder Working Group

…, K Koch, JS Kwon, L Lazaro… - American Journal of …, 2018 - Am Psychiatric Assoc
Objective: Brain imaging studies of structural abnormalities in OCD have yielded
inconsistent results, partly because of limited statistical power, clinical heterogeneity, and …

Subcortical brain volume, regional cortical thickness, and cortical surface area across disorders: findings from the ENIGMA ADHD, ASD, and OCD working groups

…, J Kuntsi, G Kvale, JS Kwon, L Lázaro… - American Journal of …, 2020 - Am Psychiatric Assoc
Objective: Attention deficit hyperactivity disorder (ADHD), autism spectrum disorder (ASD),
and obsessive-compulsive disorder (OCD) are common neurodevelopmental disorders that …

[HTML][HTML] Impact of the COVID-19 pandemic on the mental health of the general population and health care workers

…, D Gracia, M Martín, V Pérez, L Lázaro… - Revista Española de …, 2023 - ncbi.nlm.nih.gov
The Health Sciences Foundation has assembled a multi-disciplinary group around a series
of questions about the impact of the COVID-19 pandemic on the mental health of the general …

A cross-sectional and follow-up voxel-based morphometric MRI study in adolescent anorexia nervosa

J Castro-Fornieles, N Bargalló, L Lázaro… - Journal of psychiatric …, 2009 - Elsevier
The objective was to examine whether cerebral volumes are reduced, and in what regions,
in adolescents with anorexia nervosa and to study changes after nutritional recovery. Twelve …

Subcortical volumes across the lifespan: Data from 18,605 healthy individuals aged 3–90 years

…, J Kuntsi, J Lagopoulos, L Lázaro… - Human brain …, 2022 - Wiley Online Library
Age has a major effect on brain volume. However, the normative studies available are
constrained by small sample sizes, restricted age coverage and significant methodological …

Frequency, risk factors, clinical characteristics, and outcomes of spontaneous pneumothorax in patients with coronavirus disease 2019: a case-control, emergency …

…, MLL Grima, MÁJ Gómez, J Millán, LS Lázaro… - Chest, 2021 - Elsevier
Background Recent reports of patients with coronavirus disease 2019 (COVID-19) developing
pneumothorax correspond mainly to case reports describing mechanically ventilated …