User profiles for L. M. Thornton

Laura M Thornton

professor of psychiatry, university of north carolina at chapel hill
Verified email at med.unc.edu
Cited by 21774

The heritability of eating disorders: methods and current findings

LM Thornton, SE Mazzeo, CM Bulik - Behavioral neurobiology of eating …, 2011 - Springer
Family, twin, and adoption studies of anorexia nervosa (AN), bulimia nervosa (BN), binge-eating
disorder (BED), and the proposed purging disorder presentation (PD) have consistently …

Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa

HJ Watson, Z Yilmaz, LM Thornton, C Hübel… - Nature …, 2019 - nature.com
Characterized primarily by a low body-mass index, anorexia nervosa is a complex and
serious illness 1 , affecting 0.9–4% of women and 0.3% of men 2 , 3 – 4 , with twin-based …

Stressful life events and previous episodes in the etiology of major depression in women: an evaluation of the “kindling” hypothesis

KS Kendler, LM Thornton… - American Journal of …, 2000 - Am Psychiatric Assoc
OBJECTIVE: Although previous evidence has suggested that the etiologic role of stressful
life events in major depression is reduced in recurrent versus first-onset cases, this question …

The anorexia nervosa genetics initiative (ANGI): overview and methods

LM Thornton, MA Munn-Chernoff, JH Baker… - Contemporary Clinical …, 2018 - Elsevier
Background Genetic factors contribute to anorexia nervosa (AN); and the first genome-wide
significant locus has been identified. We describe methods and procedures for the Anorexia …

Gender differences in the rates of exposure to stressful life events and sensitivity to their depressogenic effects

KS Kendler, LM Thornton… - American Journal of …, 2001 - Am Psychiatric Assoc
OBJECTIVE: Women are at greater risk for major depression than men. The authors sought
to determine whether the gender difference in prevalence for major depression was due to …

Genetic risk, number of previous depressive episodes, and stressful life events in predicting onset of major depression

KS Kendler, LM Thornton… - American Journal of …, 2001 - Am Psychiatric Assoc
OBJECTIVE: The association between stressful life events and the onset of major depression
decreases as the number of previous depressive episodes increases. How do genetic risk …

Psychologic intervention improves survival for breast cancer patients: a randomized clinical trial

…, DM Golden‐Kreutz, CF Emery, LM Thornton… - Cancer, 2008 - Wiley Online Library
BACKGROUND. The question of whether stress poses a risk for cancer progression has
been difficult to answer. A randomized clinical trial tested the hypothesis that cancer patients …

Early impact of COVID‐19 on individuals with self‐reported eating disorders: A survey of~ 1,000 individuals in the United States and the Netherlands

…, HJ Watson, LM Thornton… - … Journal of Eating …, 2020 - Wiley Online Library
Objective We evaluated the early impact of COVID‐19 on people with self‐reported eating
disorders. Method Participants in the United States (US, N = 511) and the Netherlands (NL, N …

Symptom fluctuation in eating disorders: correlates of diagnostic crossover

F Tozzi, LM Thornton, KL Klump… - American Journal of …, 2005 - Am Psychiatric Assoc
OBJECTIVE: The course of anorexia nervosa often includes the emergence of bulimic
symptoms and a crossover to the full syndrome of bulimia nervosa. However, clinicians’ ability to …

A genome-wide association study of anorexia nervosa

…, JAB Floyd, LM Thornton, LM Huckins… - Molecular …, 2014 - nature.com
Anorexia nervosa (AN) is a complex and heritable eating disorder characterized by
dangerously low body weight. Neither candidate gene studies nor an initial genome-wide …