[PDF][PDF] Chemokine receptor redundancy and specificity are context dependent
DP Dyer, L Medina-Ruiz, R Bartolini, F Schuette… - Immunity, 2019 - cell.com
Currently, we lack an understanding of the individual and combinatorial roles for chemokine
receptors in the inflammatory process. We report studies on mice with a compound deletion …
receptors in the inflammatory process. We report studies on mice with a compound deletion …
[PDF][PDF] Chemokine CXCL4 interactions with extracellular matrix proteoglycans mediate widespread immune cell recruitment independent of chemokine receptors
…, A Chevigne, CE Hughes, L Medina-Ruiz… - Cell Reports, 2023 - cell.com
Leukocyte recruitment from the vasculature into tissues is a crucial component of the immune
system but is also key to inflammatory disease. Chemokines are central to this process but …
system but is also key to inflammatory disease. Chemokines are central to this process but …
T-cell–derived miRNA-214 mediates perivascular fibrosis in hypertension
…, M Nowak, AND Cat, L Medina-Ruiz… - Circulation …, 2020 - Am Heart Assoc
Rationale: Despite increasing understanding of the prognostic importance of vascular stiffening
linked to perivascular fibrosis in hypertension, the molecular and cellular regulation of …
linked to perivascular fibrosis in hypertension, the molecular and cellular regulation of …
Arabidopsis RUGOSA2 encodes an mTERF family member required for mitochondrion, chloroplast and leaf development
…, E Graciá‐Martínez, L Medina‐Ruiz… - The Plant …, 2011 - Wiley Online Library
Little is known about the mechanisms that control transcription of the mitochondrial and
chloroplastic genomes, and their interplay within plant cells. Here, we describe the positional …
chloroplastic genomes, and their interplay within plant cells. Here, we describe the positional …
Analysis of combinatorial chemokine receptor expression dynamics using multi-receptor reporter mice
… Copyright Medina- Ruiz et al. This article is distributed under the terms of the Creative
Commons Attribution License, which permits unrestricted use and redistribution provided that the …
Commons Attribution License, which permits unrestricted use and redistribution provided that the …
[HTML][HTML] The atypical chemokine receptor Ackr2 constrains NK cell migratory activity and promotes metastasis
…, M Pingen, CL Burt, KM Lee, L Medina-Ruiz… - The Journal of …, 2018 - journals.aai.org
Chemokines have been shown to be essential players in a range of cancer contexts. In this
study, we demonstrate that mice deficient in the atypical chemokine receptor Ackr2 display …
study, we demonstrate that mice deficient in the atypical chemokine receptor Ackr2 display …
[HTML][HTML] IL-6 and TGF-β-secreting adoptively-transferred murine mesenchymal stromal cells accelerate healing of psoriasis-like skin inflammation and upregulate IL …
N Cuesta-Gomez, L Medina-Ruiz, GJ Graham… - International Journal of …, 2023 - mdpi.com
Mesenchymal stromal cells (MSC) show promise as cellular therapeutics. Psoriasis is a
chronic inflammatory disease affecting the skin and the joints. Injury, trauma, infection and …
chronic inflammatory disease affecting the skin and the joints. Injury, trauma, infection and …
A randomized trial-intensive treatment based in ivermectin and iota-carrageenan as pre-exposure prophylaxis for COVID-19 in healthcare agents
RE Chahla, L Medina Ruiz, ES Ortega, MF Morales… - MedRxiv, 2021 - medrxiv.org
Key Point IMPORTANCE The emergency of COVID-19 requires the implementation of urgent
strategies to prevent the spread of the disease, mainly in health personnel, who are the …
strategies to prevent the spread of the disease, mainly in health personnel, who are the …
[HTML][HTML] Maraviroc prevents HCC development by suppressing macrophages and the liver progenitor cell response in a murine chronic liver disease model
…, J Fernández-Irigoyen, E Santamaría, L Medina-Ruiz… - Cancers, 2021 - mdpi.com
Simple Summary Liver stem cells and activated macrophages have been implicated as
contributors to liver cancer; hence, reducing their abundance is a potential avenue for therapy. In …
contributors to liver cancer; hence, reducing their abundance is a potential avenue for therapy. In …
[HTML][HTML] CXCR2 deficient mice display macrophage-dependent exaggerated acute inflammatory responses
… The original version of this Article contained a typographical error in the spelling of the
author Laura Medina-Ruiz, which was incorrectly given as Laura Medina Ruiz. This has now …
author Laura Medina-Ruiz, which was incorrectly given as Laura Medina Ruiz. This has now …