[PDF][PDF] Genotype–phenotype correlation in hepatocellular adenoma: new classification and relationship with HCC

…, D Wendum, L Chiche, M Fabre, L Mellottee… - …, 2006 - Wiley Online Library
Hepatocellular adenomas are benign tumors that can be difficult to diagnose. To refine their
classification, we performed a comprehensive analysis of their genetic, pathological, and …

Xenobiotic-metabolizing enzymes and transporters in the normal human brain: regional and cellular mapping as a basis for putative roles in cerebral function

…, M Diry, V Sazdovitch, O Cloarec, L Mellottée… - Drug Metabolism and …, 2009 - ASPET
Cytochrome P450 (P450) enzymes and ATP-binding cassette (ABC) transporters modulate
the transport and metabolism of both endogenous and exogenous substrates and could play …

Spectrum of HNF1A Somatic Mutations in Hepatocellular Adenoma Differs From That in Patients With MODY3 and Suggests Genotoxic Damage

E Jeannot, L Mellottee, P Bioulac-Sage, C Balabaud… - Diabetes, 2010 - Am Diabetes Assoc
OBJECTIVE Maturity onset diabetes of the young type 3 (MODY3) is a consequence of
heterozygous germline mutation in HNF1A. A subtype of hepatocellular adenoma (HCA) is also …

Inflammatory syndrome with liver adenomatosis: the beneficial effects of surgical management

AS Cunha, JF Blanc, E Lazaro, L Mellottee, B Le Bail… - Gut, 2007 - gut.bmj.com
… 90 mg/l, fibrinogen 7 g/l, sedimentation rate 106 mm and haptoblobin 2.9 g/l. Investigations
… normalised: the red blood cell count was 4.4 T/l, haemoglobin 12.7 g/dl, hematocrite 39.2%, …

[HTML][HTML] Bacterial origins of thymidylate metabolism in Asgard archaea and Eukarya

J Filée, HF Becker, L Mellottee, RZ Eddine, Z Li… - Nature …, 2023 - nature.com
Asgard archaea include the closest known archaeal relatives of eukaryotes. Here, we
investigate the evolution and function of Asgard thymidylate synthases and other folate-dependent …

[HTML][HTML] Jouvence a small nucleolar RNA required in the gut extends lifespan in Drosophila

S Soulé, L Mellottée, A Arab, C Chen… - Nature …, 2020 - nature.com
l, m ISH on ovaries. Stacks of confocal images showing jou expression in the nucleolus
of Control (l) and absent in deletion (m). n Schematic drawing of the gut showing its different …

Similar tumor suppressor gene alteration profiles in asbestos-induced murine and human mesothelioma

…, A Renier, L Kheuang, V Abramowski, L Mellotte… - Cell cycle, 2005 - Taylor & Francis
The status of tumor suppressor genes (TSGs) relevant to human malignant mesothelioma (HMM)
pathogenesis was examined in cultures of mesothelioma cells from tumoral ascites …

No clear link between VKORC1 genetic polymorphism and the risk of venous thrombosis or peripheral arterial disease

…, MA Loriot, LA Hindorff, L Mellottee… - Thrombosis and …, 2008 - thieme-connect.com
Dear Sir, Vitamin K, discovered in the 1930s, functions as a cofactor for the posttranslational
carboxylation of glutamate residues (1). The vitamin K-epoxide reductase complex (VKOR) …

Nance-Horan-Syndrome-like 1b controls mesodermal cell migration by regulating protrusion and actin dynamics during zebrafish gastrulation

S Escot, A Elouin, L Mellottee, NB David - bioRxiv, 2023 - biorxiv.org
Cell migrations are crucial for embryonic development, wound healing, the immune
response, as well as for cancer progression. During mesenchymal cell migration, the Rac1-WAVE-…

Nhsl1b regulates mesodermal cell migration by controlling protrusion dynamics during zebrafish gastrulation

S Escot, A Elouin, L Mellottee, NB David - 2023 - hal.science
… & Solnica-Krezel, L. Initiation of convergence and extension movements of lateral …
Williams, MLK & Solnica-Krezel, L. Cellular and molecular mechanisms of convergence and …