User profiles for L. Romani

Luigina Romani

Professor of General Pathology
Verified email at unipg.it
Cited by 50842

Immunity to fungal infections

L Romani - Nature Reviews Immunology, 2011 - nature.com
Fungal diseases represent an important paradigm in immunology, as they can result from
either a lack of recognition by the immune system or overactivation of the inflammatory …

[HTML][HTML] Immunity to fungal infections

L Romani - Nature Reviews Immunology, 2004 - nature.com
The topic of immunity to fungal infections is of interest to a wide range of disciplines, from
microbiology to immunology. It is of particular interest in terms of therapy of HIV-infected …

Aspergillus fumigatus morphology and dynamic host interactions

FL Van De Veerdonk, MS Gresnigt, L Romani… - Nature Reviews …, 2017 - nature.com
Aspergillus fumigatus is an environmental filamentous fungus that can cause life-threatening
disease in immunocompromised individuals. The interactions between A. fumigatus and …

[PDF][PDF] Tryptophan catabolites from microbiota engage aryl hydrocarbon receptor and balance mucosal reactivity via interleukin-22

…, F Fallarino, A Carvalho, P Puccetti, L Romani - Immunity, 2013 - cell.com
… IL-22 production in infection, we measured IL-22 production in ex vivo cultures of gastric
specimens exposed to a physiologically relevant concentration of IAld or to supernatants of L. …

Non-redundant role of the long pentraxin PTX3 in anti-fungal innate immune response

…, G Siracusa, F Altruda, A Vecchi, L Romani… - Nature, 2002 - nature.com
Pentraxins are a superfamily of conserved proteins that are characterized by a cyclic multimeric
structure 1 . The classical short pentraxins, C-reactive protein (CRP) and serum amyloid …

IL‐23 and the Th17 pathway promote inflammation and impair antifungal immune resistance

…, RA Kastelein, M Kopf, L Romani - European journal of …, 2007 - Wiley Online Library
Although inflammation is an essential component of the protective response to fungi, its
dysregulation may significantly worsen fungal diseases. We found here that the IL‐23/IL‐17 …

Aryl hydrocarbon receptor control of a disease tolerance defence pathway

…, L Boon, M Pirro, A Iorio, B Veyret, L Romani… - Nature, 2014 - nature.com
Disease tolerance is the ability of the host to reduce the effect of infection on host fitness.
Analysis of disease tolerance pathways could provide new approaches for treating infections …

Surface hydrophobin prevents immune recognition of airborne fungal spores

…, S Paris, AA Brakhage, SV Kaveri, L Romani… - Nature, 2009 - nature.com
The air we breathe is filled with thousands of fungal spores (conidia) per cubic metre, which
in certain composting environments can easily exceed 10 9 per cubic metre. They originate …

Defective tryptophan catabolism underlies inflammation in mouse chronic granulomatous disease

L Romani, F Fallarino, A De Luca, C Montagnoli… - Nature, 2008 - nature.com
… However, IFN-γ was unable to mediate conversion of externally added l-tryptophan to l-kynurenine
by mononuclear phagocytes from p47 phox -/- mice, confirming that, in experimental …

The contribution of the Toll-like/IL-1 receptor superfamily to innate and adaptive immunity to fungal pathogens in vivo

…, A Mantovani, SM Levitz, L Romani - The Journal of …, 2004 - journals.aai.org
In vitro studies have indicated the importance of Toll-like receptor (TLR) signaling in
response to the fungal pathogens Candida albicans and Aspergillus fumigatus. However, the …