New α-(N)-heterocyclichydrazones: evaluation of anticancer, anti-HIV and antimicrobial activity

L Savini, L Chiasserini, V Travagli, C Pellerano… - European journal of …, 2004 - Elsevier
… of in vitro tumour cell growth by heterocyclichydrazones 1a–l … of in vitro tumour cell growth
by heterocyclichydrazones 2a–l … ), against which the compounds 1a–l displayed GI 50 in the …

Size-dependent oxidation in iron/iron oxide core-shell nanoparticles

L Signorini, L Pasquini, L Savini, R Carboni… - Physical Review B, 2003 - APS
We report a detailed morphological and structural characterization of iron/iron oxide core-shell
nanoparticles with x-ray diffraction and x-ray absorption spectroscopy performed at both …

Magnetothermal behavior of a nanoscale Fe/Fe oxide granular system

L Del Bianco, D Fiorani, AM Testa, E Bonetti, L Savini… - Physical Review B, 2002 - APS
The low-temperature magnetic properties of samples obtained by cold-compacting core-shell
Fe/Fe oxide nanoparticles have been investigated, and their dependence on the structure, …

Network analysis of Italian cattle trade patterns and evaluation of risks for potential disease spread

…, A Giovannini, L Savini, D Palma, L Possenti… - Preventive veterinary …, 2009 - Elsevier
… Author links open overlay panel Fabrizio Natale a , Armando Giovannini b , Lara Savini b ,
… variable was extracted from the relevant binomial distribution: θ t ∼ B i n o m i a l n , I t N . …

Synthesis of N1-arylidene-N2-quinolyl-and N2-acrydinylhydrazones as potent antimalarial agents active against CQ-resistant P. falciparum strains

…, M Persico, MP Romano, M Altarelli, L Savini… - Bioorganic & medicinal …, 2006 - Elsevier
A series of N1-arylidene-N2-quinolyl- and N2-acrydinylhydrazones were synthesized and
tested for their antimalarial properties. These compounds showed remarkable anti-plasmodial …

[HTML][HTML] Dynamical patterns of cattle trade movements

P Bajardi, A Barrat, F Natale, L Savini, V Colizza - PloS one, 2011 - journals.plos.org
Despite their importance for the spread of zoonotic diseases, our understanding of the dynamical
aspects characterizing the movements of farmed animal populations remains limited as …

Synthesis and anti-tubercular evaluation of 4-quinolylhydrazones

L Savini, L Chiasserini, A Gaeta, C Pellerano - Bioorganic & medicinal …, 2002 - Elsevier
A series of 4-quinolylhydrazones were synthesized and tested against Mycobacterium
tuberculosis H37Rv. Preparation of the title compounds was achieved by reaction of 4-…

Specific targeting of acetylcholinesterase and butyrylcholinesterase recognition sites. Rational design of novel, selective, and highly potent cholinesterase inhibitors

L Savini, A Gaeta, C Fattorusso… - Journal of Medicinal …, 2003 - ACS Publications
Tacrine-based AChE and BuChE inhibitors were designed by investigating the topology of
the active site gorge of the two enzymes. The homobivalent ligands characterized by a …

Optimizing surveillance for livestock disease spreading through animal movements

P Bajardi, A Barrat, L Savini… - Journal of the Royal …, 2012 - royalsocietypublishing.org
The spatial propagation of many livestock infectious diseases critically depends on the animal
movements among premises; so the knowledge of movement data may help us to detect, …

[HTML][HTML] The dimer-monomer equilibrium of SARS-CoV-2 main protease is affected by small molecule inhibitors

…, A Palumbo Piccionello, C Petrillo, L Savini… - Scientific Reports, 2021 - nature.com
The maturation of coronavirus SARS-CoV-2, which is the etiological agent at the origin of
the COVID-19 pandemic, requires a main protease M pro to cleave the virus-encoded …