… Trussell and colleagues have shown that in nMAG, depression observed with high-frequency
stimuli may be due in part to AMPA receptor desensitization (34, 107), although the extent …

The action potential generally begins in the axon initial segment (AIS), a principle confirmed
by 60 years of research; however, the most recent advances have shown that a very rich …

… Glutamatergic EPSPs rise and decay within l-Zms, both in avian nucleus magnocellularis …
Raman IM, Trussell LO: The kinetics of the response to glutamate and kainate in neurons of the …

… (lower panel), we show that this small phase of kainate (Raman and Trussell, 1992). When
… synaptic potentials for short periods at rates up to 500 Hz (Zhang and Trussell, unpublished …

Responses of excitatory amino acid receptors to rapidly applied glutamate were measured
in outside-out membrane patches from chick spinal neurons. The peak current varied with …

At fast CNS synapses, the role of asynchronous release following initial synchronous release
is poorly understood. We examined the contribution of asynchronous release to GABAergic …

In the dorsal cochlear nucleus, long-term synaptic plasticity can be induced at the parallel
fiber inputs that synapse onto both fusiform principal neurons and cartwheel feedforward …

Glycine and GABA A (γ-aminobutyric acid A) receptors are inhibitory neurotransmitter-gated
Cl - channels localized in postsynaptic membranes. In some cases, GABA A receptors are …

Activation of presynaptic ion channels alters the membrane potential of nerve terminals,
leading to changes in transmitter release. To study the relationship between resting potential …

Synapses may undergo long-term increases or decreases in synaptic strength dependent
on critical differences in the timing between pre-and postsynaptic activity. Such spike-timing-…