User profiles for L.J. Dursi
 | L. Jonathan DursiNVIDIA Verified email at dursi.ca Cited by 5620 |
Detecting DNA cytosine methylation using nanopore sequencing
In nanopore sequencing devices, electrolytic current signals are sensitive to base modifications,
such as 5-methylcytosine (5-mC). Here we quantified the strength of this effect for the …
such as 5-methylcytosine (5-mC). Here we quantified the strength of this effect for the …
SciNet: lessons learned from building a power-efficient top-20 system and data centre
…, J Dempsey, CH Yu, J Chen, LJ Dursi… - Journal of physics …, 2010 - iopscience.iop.org
SciNet, one of seven regional HPC consortia operating under the Compute Canada
umbrella, runs Canada's first and third fastest computers (as of June 2010) in a state-of-the-art, …
umbrella, runs Canada's first and third fastest computers (as of June 2010) in a state-of-the-art, …
[PDF][PDF] GA4GH: International policies and standards for data sharing across genomic research and healthcare
The Global Alliance for Genomics and Health (GA4GH) aims to accelerate biomedical
advances by enabling the responsible sharing of clinical and genomic data through both …
advances by enabling the responsible sharing of clinical and genomic data through both …
Draping of cluster magnetic fields over bullets and bubbles—morphology and dynamic effects
LJ Dursi, C Pfrommer - The Astrophysical Journal, 2008 - iopscience.iop.org
High-resolution X-ray observations have revealed cavities and “cold fronts” with sharp edges
in temperature and density within galaxy clusters. Their presence poses a puzzle, since …
in temperature and density within galaxy clusters. Their presence poses a puzzle, since …
Nanocall: an open source basecaller for Oxford Nanopore sequencing data
Motivation The highly portable Oxford Nanopore MinION sequencer has enabled new
applications of genome sequencing directly in the field. However, the MinION currently relies on a …
applications of genome sequencing directly in the field. However, the MinION currently relies on a …
On validating an astrophysical simulation code
We present a case study of validating an astrophysical simulation code. Our study focuses
on validating FLASH, a parallel, adaptive-mesh hydrodynamics code for studying the …
on validating FLASH, a parallel, adaptive-mesh hydrodynamics code for studying the …
Mapping initial hydrostatic models in Godunov codes
We look in detail at the process of mapping an astrophysical initial model from a stellar
evolution code onto the computational grid of an explicit, Godunov-type code while maintaining …
evolution code onto the computational grid of an explicit, Godunov-type code while maintaining …
[HTML][HTML] Algorithmic comparisons of decaying, isothermal, supersonic turbulence
Context. Simulations of astrophysical turbulence have reached such a level of sophistication
that quantitative results are now starting to emerge. However, contradicting results have …
that quantitative results are now starting to emerge. However, contradicting results have …
Recombinations to the Rydberg states of hydrogen and their effect during the cosmological recombination epoch
In this paper we discuss the effect of recombinations to highly excited states (n > 100) in
hydrogen during the cosmological recombination epoch. For this purpose, we developed a new …
hydrogen during the cosmological recombination epoch. For this purpose, we developed a new …
[HTML][HTML] Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples
The Cancer Genome Atlas (TCGA) and International Cancer Genome Consortium (ICGC)
curated consensus somatic mutation calls using whole exome sequencing (WES) and whole …
curated consensus somatic mutation calls using whole exome sequencing (WES) and whole …