The Alzheimer Disease Genetics Consortium (ADGC) performed a genome-wide association
study of late-onset Alzheimer disease using a three-stage design consisting of a discovery …

With more than 4 million Alzheimer's victims nationwide, there is intense research to elucidate
the relationship among the hallmarks of the disease, amyloid plaques, neurofibrillary …

Objective: To explore the impact of apoE-4 on Alzheimer's disease (AD) and its age at onset.
Design: A genetic linkage study using affected relative pairs, predominantly siblings. Setting…

Objectives: To determine whether genotypes at CLU, PICALM, and CR1 confer risk for
Alzheimer disease (AD) and whether risk for AD associated with these genes is influenced by …

Objective: To assess empirically the competency of patients with Alzheimer's disease (AD) to
consent to medical treatment under different legal standards (LSs). Design: Comparison of …

… Marson D., Ingram K, Cody H, Harrell L. Assessing the … Marson D, Cody H, Ingram K, Harrell
L. Neuropsychological correlates of … Marson D, Ingram K, Hazlett G, Duke L, Harrell L. How …

Objective To investigate financial capacity in patients with Alzheimer disease (AD) using a
new theoretical model and prototype psychometric instrument. Design Cross-sectional …

Psychological, social, and health variables were compared in 175 Black and White family
caregivers of patients with dementia and 175 Black and White noncaregivers. Caregivers and …

… institutions, Baltimore, Md (Drs Bassett and Folstein); the Department of Epidemiology,
School of Public Health (Dr Go), the Department of Neurology, School of Medicine (Dr Harrell), …

Alzheimer's disease (AD) is a devastating neurodegenerative disorder of late life with
complex inheritance. Mutations in three known genes lead to the rare early-onset autosomal …