Context-dependent activation of SIRT3 is necessary for anchorage-independent survival and metastasis of ovarian cancer cells

…, BL Worley, S Shimko, DH Shin, LTC Crawford… - Oncogene, 2020 - nature.com
Tumor cells must alter their antioxidant capacity for maximal metastatic potential. Yet the
antioxidant adaptations required for ovarian cancer transcoelomic metastasis, which is the …

[HTML][HTML] Sex differences in tolerance to delta-9-tetrahydrocannabinol in mice with cisplatin-evoked chronic neuropathic pain

AN Henderson-Redmond, LTC Crawford… - Frontiers in molecular …, 2021 - frontiersin.org
Tolerance to the pain-relieving effects of cannabinoids limits the therapeutic potential of these
drugs in patients with chronic pain. Recent preclinical research with rodents and clinical …

Optimization of extracellular flux assay to measure respiration of anchorage-independent tumor cell spheroids

…, BL Worley, C Stump, SS Shimko, LTC Crawford… - Bio …, 2022 - bio-protocol.org
Three-dimensional (3D) cell culture models are widely used in tumor studies to more
accurately reflect cell-cell interactions and tumor growth conditions in vivo. 3D anchorage-…

[HTML][HTML] Decursinol-mediated antinociception and anti-allodynia in acute and neuropathic pain models in male mice: Tolerance and receptor profiling

LTC Crawford, S Kim, D Karelia… - Frontiers in …, 2022 - frontiersin.org
Korean scientists have shown that oral administration of Angelica gigas Nakai (AGN) root
alcoholic extract and the metabolite of its pyranocoumarins, decursinol, have antinociceptive …

Sperm associated antigen 7 is activated by T3 during Xenopus tropicalis metamorphosis via a thyroid hormone response element within the first intron

L Fu, LT Crawford, A Tong, N Luu… - Development …, 2022 - Wiley Online Library
Thyroid hormone (T3) affects many diverse physiological processes such as metabolism,
organogenesis, and growth. The two highly related frog species, diploid Xenopus tropicalis …

[BOOK][B] Investigating beneficial microbes from marsh ecosystems for sustainable agricultural and environmental applications

PT McKenzie-Reynolds - 2017 - search.proquest.com
Microorganisms are often thought of as pests and harmful organisms, but there are numerous
important microbes that are beneficial to both human and environmental health. Some …