Estrogen receptor (ER) and NFκB are two widely expressed, pleiotropic transcription factors
that have been shown to interact and affect one another’s activity. While the ability of ER to …

The clinical use of cisplatin is highly limited, because of its renal toxicity. In this study, the
protective effect of grape seed proanthocyanidin extract (GSPE) against cisplatin-induced …

In breast tumors, activation of the nuclear factor κB (NFκB) pathway promotes survival,
migration, invasion, angiogenesis, stem cell-like properties, and resistance to therapy—all …

Circulating tumor cell (CTC) clusters mediate metastasis at a higher efficiency and are associated
with lower overall survival in breast cancer compared to single cells. Combining single-…

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused the pandemic
of the coronavirus induced disease 2019 (COVID-19) with evolving variants of concern. …

Triple-negative breast cancer (TNBC) is one of the most aggressive and metastatic breast
cancer subtypes lacking targeted therapy. Our recent work demonstrated that circulating tumor …

Tumor-initiating cells with reprogramming plasticity or stem-progenitor cell properties (stemness)
are thought to be essential for cancer development and metastatic regeneration in …

This study discovers that dynamic loss of terminal sialylation in glycoproteins of CTC clusters
contributes to the fate of cellular dormancy, advantageous evasion to chemotherapy, and …

Mathematical modelling has been used to study tumor-immune cell interaction. Some models
were proposed to examine the effect of circulating lymphocytes, natural killer cells, and …

The synthetic food preservative sodium benzoate (SB) is widely used in both food and
pharmaceutical industries. A growing body of evidence highlights the adverse effects of SB on …