Pigs are a valuable human biomedical model and an important protein source supporting
global food security. The transcriptomes of peripheral blood immune cells in pigs were defined …

Humanized mice (hu-mice) that feature a functional human immune system have fundamentally
changed the study of human pathogens and disease. They can be used to model …

Two lineages of influenza D virus (IDV) have been found to infect cattle and promote bovine
respiratory disease complex, one of the most commonly diagnosed causes of morbidity and …

Neutrophils are vital components of the immune system for limiting the invasion and proliferation
of pathogens in the body. Surprisingly, the functional annotation of porcine neutrophils …

Background Humanized mice featuring a functional human immune system are an important
pre-clinical model for examining immune responses to human-specific pathogens. This …

Background While the translatability of gut microbiome studies utilizing animal models to
humans has proven difficult, studying the gut microbiome directly in humans is also challenging …

The HIV-1 pandemic is a consequence of the cross-species transmission of simian
immunodeficiency virus in wild chimpanzees (SIVcpz) to humans. Our previous study demonstrated …

The agriculture genomics community has numerous data submission standards available
but little experience describing and storing single-cell (eg, scRNAseq) data. Other single-cell …

The transcriptome of porcine peripheral blood mononuclear cells (PBMC) at single cell (sc)
resolution is well described, but little is understood about the cis-regulatory mechanism …

Characterizing the transmitted/founder (T/F) viruses of multi-variant SIV infection may shed
new light on the understanding of mucosal transmission. We intrarectally inoculated six …