[PDF][PDF] Establishment of the vertebrate body plan: Rethinking gastrulation through stem cell models of early embryogenesis
B Steventon, L Busby, AM Arias - Developmental Cell, 2021 - cell.com
A striking property of vertebrate embryos is the emergence of a conserved body plan across
a wide range of organisms through the process of gastrulation. As the body plan unfolds, …
a wide range of organisms through the process of gastrulation. As the body plan unfolds, …
Tissue tectonics and the multi-scale regulation of developmental timing
L Busby, B Steventon - Interface Focus, 2021 - royalsocietypublishing.org
Development encompasses processes that occur at multiple length scales, including gene-regulatory
interactions, cell movements and reorganization, cell signalling and growth. It is …
interactions, cell movements and reorganization, cell signalling and growth. It is …
Intrinsic and extrinsic cues time somite progenitor contribution to the vertebrate primary body axis
L Busby, GS Nájera, BJ Steventon - Elife, 2024 - elifesciences.org
During embryonic development, the timing of events at the cellular level must be coordinated
across multiple length scales to ensure the formation of a well-proportioned body plan. This …
across multiple length scales to ensure the formation of a well-proportioned body plan. This …
[HTML][HTML] Quantitative experimental embryology: a modern classical approach
L Busby, D Saunders, G Serrano Nájera… - Journal of …, 2022 - mdpi.com
Experimental Embryology is often referred to as a classical approach of developmental
biology that has been to some extent replaced by the introduction of molecular biology and …
biology that has been to some extent replaced by the introduction of molecular biology and …
A population intrinsic timer controls Hox gene expression and cell dispersion during progenitor addition to the body axis
L Busby, G Serrano Nájera, B Steventon - BioRxiv, 2023 - biorxiv.org
During embryonic development, the timing of events at the cellular level must be coordinated
across multiple length scales to ensure the formation of a well-proportioned body plan. This …
across multiple length scales to ensure the formation of a well-proportioned body plan. This …
Sonic hedgehog specifies flight feather positional information in avian wings
L Busby, C Aceituno, C McQueen, CA Rich… - …, 2020 - journals.biologists.com
Classical tissue recombination experiments performed in the chick embryo provide evidence
that signals operating during early limb development specify the position and identity of …
that signals operating during early limb development specify the position and identity of …
Hybridization chain reaction for quantitative and multiplex imaging of gene expression in amphioxus embryos and adult tissues
TGR Andrews, G Gattoni, L Busby… - In Situ Hybridization …, 2020 - Springer
In situ hybridization (ISH) methods remain the most popular approach for profiling the
expression of a gene at high spatial resolution and have been broadly used to address many …
expression of a gene at high spatial resolution and have been broadly used to address many …
Multi-scalar mechanisms timing axial progenitor contribution to the vertebrate body axis
L Busby - 2023 - repository.cam.ac.uk
Timing is a fundamental feature of embryogenesis: the embryos of a given species develop
with reproducible timing and a precise ordering of events. The underlying mechanisms that …
with reproducible timing and a precise ordering of events. The underlying mechanisms that …
A positional information gradient of sonic hedgehog is required for flight feather formation in avian wings
L Busby, C Aceituno, C McQueen, CA Rich, MA Ros… - bioRxiv, 2019 - biorxiv.org
Flight is a triumph of evolution that enabled the radiation and success of birds. A crucial step
was the development of forelimb flight feathers that may have evolved for courtship or …
was the development of forelimb flight feathers that may have evolved for courtship or …
The evolution of somitogenesis: Mechanisms of paraxial mesoderm elongation in zebrafish and other vertebrates
L Thomson - 2021 - repository.cam.ac.uk
In vertebrate embryos, a process called somitogenesis lays the foundations of the adult
spine. This process involves elongation and segmentation of the paraxial mesoderm to form …
spine. This process involves elongation and segmentation of the paraxial mesoderm to form …