Recent advances in sequencing and informatic technologies have led to a deluge of publicly
available genomic data. While it is now relatively easy to sequence, assemble, and identify …

Key message Nicotiana benthamiana acylsugar acyltransferase (ASAT) is required for
protection against desiccation and insect herbivory. Knockout mutations provide a new resource …

Large enzyme families catalyze metabolic diversification by virtue of their ability to use
diverse chemical scaffolds. How enzyme families attain such functional diversity is not clear. …

Plant responses to environmental change are mediated via changes in cellular metabolomes.
However, <5% of signals obtained from liquid chromatography tandem mass spectrometry …

Polyamines are important metabolites in plant development and abiotic and biotic stress
responses. Copper-containing amine oxidases (CuAOs) are involved in the regulation of …

Pyrrolizidine alkaloids (PAs) are a typical class of plant secondary metabolites that are
constitutively produced as part of the plant’s chemical defense. While roots are a well-established …

Acylsugars are a class of plant defense compounds produced across many distantly related
families. Members of the horticulturally important morning glory (Convolvulaceae) family …

Pyrrolizidine alkaloids ( PA s) are toxic secondary metabolites that are found in several
distantly related families of the angiosperms. The first specific step in PA biosynthesis is …

Plants produce a diverse array of compounds through an extensive, evolutionarily malleable
network of metabolic pathways. These metabolites are typically classified into two types—…

Comfrey is a medicinal plant, extracts of which are traditionally used for the treatment of
painful inflammatory muscle and joint problems, because the plant contains allantoin and …