Excess lipid accumulation in peripheral tissues is a key feature of many metabolic diseases.
Therefore, techniques for imaging and quantifying lipids in various tissues are important for …

Many important cell types in adult vertebrates have a mesenchymal origin, including fibroblasts
and vascular mural cells. Although their biological importance is undisputed, the level of …

Angiogenesis, the process by which new blood vessels arise from preexisting ones, is critical
for embryonic development and is an integral part of many disease processes. Recent …

A and B, Comparison of ACE2 expression in human primary epithelial cells and ECs using
total RNA sequencing data from the ENCODE database shows low or absent expression in …

The prevalence of type 2 diabetes is rapidly increasing, with severe socioeconomic impacts
1 , 2 . Excess lipid deposition in peripheral tissues impairs insulin sensitivity and glucose …

Fibroblasts, the principal cell type of connective tissue, secrete extracellular matrix components
during tissue development, homeostasis, repair and disease. Despite this crucial role, …

Accumulating clinical observations suggest pathogenesis beyond viral pneumonia and its
secondary consequences in COVID-19 patients. In particular, many patients develop profound …

Loss-of-function (LOF) mutations in the endothelial cell (EC)-enriched gene endoglin (ENG)
cause the human disease hereditary haemorrhagic telangiectasia-1, characterized by …

Humanized mouse models and mouse-adapted SARS-CoV-2 virus are increasingly used to
study COVID-19 pathogenesis, so it is important to learn where the SARS-CoV-2 receptor …

Leptomeninges, consisting of the pia mater and arachnoid, form a connective tissue investment
and barrier enclosure of the brain. The exact nature of leptomeningeal cells has long …