[HTML][HTML] Triacylglycerol synthesis enhances macrophage inflammatory function

A Castoldi, LB Monteiro… - Nature …, 2020 - nature.com
Foamy macrophages, which have prominent lipid droplets (LDs), are found in a variety of
disease states. Toll-like receptor agonists drive triacylglycerol (TG)-rich LD development in …

[PDF][PDF] Lipolysis-derived linoleic acid drives beige fat progenitor cell proliferation

I Abe, Y Oguri, ARP Verkerke, LB Monteiro, CM Knuth… - Developmental cell, 2022 - cell.com
De novo beige adipocyte biogenesis involves the proliferation of progenitor cells in white
adipose tissue (WAT); however, what regulates this process remains unclear. Here, we report …

Leptin signaling suppression in macrophages improves immunometabolic outcomes in obesity

LB Monteiro, JS Prodonoff, C Favero de Aguiar… - Diabetes, 2022 - Am Diabetes Assoc
Obesity is a major concern for global health care systems. Systemic low-grade inflammation
in obesity is a major risk factor for insulin resistance. Leptin is an adipokine secreted by the …

[PDF][PDF] Tissue-specific metabolic profile drives iNKT cell function during obesity and liver injury

…, MA Pretti, GG Davanzo, BG Castelucci, LB Monteiro… - Cell reports, 2023 - cell.com
B iNKT cell activation in vivo B iNKT cell activation ex-vivo B NKT10 induction … B Glucose
tolerance test (GTT) B Acute liver injury model B Serum transferase and transaminase activity B

SARS-CoV-2 uses CD4 to infect T helper lymphocytes

…, SP Muraro, TL Knittel, VO Boldrini, LB Monteiro… - Elife, 2023 - elifesciences.org
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the agent of a major
global outbreak of respiratory tract disease known as Coronavirus Disease 2019 (COVID-19)…

[PDF][PDF] Elevated glucose levels favor SARS-CoV-2 infection and monocyte response through a HIF-1α/glycolysis-dependent axis

AC Codo, GG Davanzo, L de Brito Monteiro… - Cell metabolism, 2020 - cell.com
COVID-19 can result in severe lung injury. It remained to be determined why diabetic individuals
with uncontrolled glucose levels are more prone to develop the severe form of COVID-…

[HTML][HTML] Using flow cytometry for mitochondrial assays

L de Brito Monteiro, GG Davanzo, CF de Aguiar… - MethodsX, 2020 - Elsevier
The understanding of how different cell types adapt their metabolism in the face of challenges
has been attracting the attention of researchers for many years. Recently, immunologists …

[PDF][PDF] Acid pH increases SARS-CoV-2 infection and the risk of death by COVID-19

…, LKK Ferreira, GG Davanzo, LB Monteiro… - Frontiers in …, 2021 - repositorio.usp.br
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can infect a broad
range of human tissues by using the host receptor angiotensin-converting enzyme 2 (ACE2). …

Leptin in the regulation of the immunometabolism of adipose tissue-macrophages

L Monteiro, JAS Pereira, L Palhinha… - Journal of leukocyte …, 2019 - academic.oup.com
… A study by Maya-Monteiro and colleagues showed that leptin induces the activation of
mTORC1, leading to the formation of lipid droplets. The newly formed lipid bodies were sites of 5-…

[HTML][HTML] Acid pH increases SARS-CoV-2 infection and the risk of death by COVID-19

…, LKK Ferreira, GG Davanzo, L Brito Monteiro… - Frontiers in …, 2021 - frontiersin.org
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can infect a broad
range of human tissues by using the host receptor angiotensin-converting enzyme 2 (ACE2). …