Absolute and relative risks of kidney outcomes associated with lithium vs valproate use in Sweden

A Bosi, CM Clase, L Ceriani, A Sjölander… - JAMA Network …, 2023 - jamanetwork.com
Importance Among patients with bipolar disorder, discordant findings have been published
on the nephrotoxic effects of lithium therapy. Objective To quantify absolute and relative risks …

[HTML][HTML] The glycocalyx affects the mechanotransductive perception of the topographical microenvironment

…, C Piazzoni, F Borghi, A Previdi, L Ceriani… - Journal of …, 2022 - Springer
The cell/microenvironment interface is the starting point of integrin-mediated mechanotransduction,
but many details of mechanotransductive signal integration remain elusive due to the …

[HTML][HTML] In vitro and in vivo activity of lucitanib in FGFR1/2 amplified or mutated cancer models

…, R Chilà, E Bello, M Zucchetti, M Zangarini, L Ceriani… - Neoplasia, 2017 - Elsevier
The fibroblast growth factor receptor (FGFR) pathway has been implicated both as an escape
mechanism from anti-angiogenic therapy and as a driver oncogene in different tumor types…

Quantification of trabectedin in human plasma: Validation of a high-performance liquid chromatography–mass spectrometry method and its application in a clinical …

M Zangarini, L Ceriani, F Sala, E Marangon… - … of Pharmaceutical and …, 2014 - Elsevier
A rapid, sensitive and specific HPLC–MS/MS method was developed and validated for the
quantification of trabectedin in human plasma after using deuterated trabectedin as Internal …

HPLC–MS/MS method to measure trabectedin in tumors: Preliminary PK study in a mesothelioma xenograft model

L Ceriani, M Ferrari, M Zangarini, SA Licandro, E Bello… - Bioanalysis, 2015 - Future Science
Background: Trabectedin is an anticancer agent registered for the second-line treatment of
soft tissue sarcoma and ovarian cancer. No preclinical data are available on its tumor …

Quality of laboratory biomarker monitoring during treatment with lithium in patients with bipolar disorder

A Bosi, L Ceriani, CG Elinder, R Bellocco… - Bipolar …, 2023 - Wiley Online Library
Background Clinical guidelines recommend monitoring of creatinine and lithium throughout
treatment with lithium. We here assessed the extent to which this occurs in healthcare in …

HPLC‐MS/MS method for quantitative determination of the novel dual inhibitor of FGF and VEGF receptors E‐3810 in tumor tissues from xenograft mice and human …

M Zangarini, L Ceriani, E Bello, G Damia… - Journal of Mass …, 2014 - Wiley Online Library
We developed and validated a high‐performance liquid chromatography–tandem mass
spectrometry analytical method to measure E‐3810, a novel dual inhibitor of fibroblast growth …

The glycocalyx affects force loading-dependent mechanotransductive topography sensing at the nanoscale

…, M D'Urso, C Piazzoni, F Borghi, A Previdi, L Ceriani… - bioRxiv, 2021 - biorxiv.org
The cell/microenvironment interface is the starting point of integrin-mediated mechanotransduction,
but many details of mechanotransductive signal integration remain elusive due to the …

MO502: Use of Lithium, Valproate and the Risk of Acute or Chronic Kidney Disease: An Observational Study From Routine Care Data

A Bosi, C Laura, E Fu, B Runesson… - Nephrology Dialysis …, 2022 - academic.oup.com
BACKGROUND AND AIMS Lithium is an established treatment for bipolar disorder and
treatment-resistant depression. Despite awareness of potential kidney damage, there is a lack of …

Exploring the in vitro and in vivo activity of lucitanib in FGFR1-amplified lung cancer models

E Bello, R Chilà, F Guffanti, M Zangarini, L Ceriani… - Cancer Research, 2014 - AACR
Lucitanib (S80881, formerly E-3810) is a novel tyrosine kinase inhibitor that selectively
inhibits vascular endothelial growth factor (VEGF) receptors 1-3 (VEGFR1-3) and fibroblast …