User profiles for Laura E. Berkowitz
Laura BerkowitzPostdoctoral Associate, Cornell University Verified email at cornell.edu Cited by 453 |
The retrosplenial-parietal network and reference frame coordination for spatial navigation.
The retrosplenial cortex is anatomically positioned to integrate sensory, motor, and visual
information and is thought to have an important role in processing spatial information and …
information and is thought to have an important role in processing spatial information and …
Anxiety-like behavior as an early endophenotype in the TgF344-AD rat model of Alzheimer's disease
Alzheimer's disease (AD) is characterized by progressive cognitive decline and the presence
of aggregates of amyloid beta (plaques) and hyperphosphorylated tau (tangles). Early …
of aggregates of amyloid beta (plaques) and hyperphosphorylated tau (tangles). Early …
Behavioral and neural subsystems of rodent exploration
Animals occupy territories in which resources such as food and shelter are often distributed
unevenly. While studies of exploratory behavior have typically involved the laboratory rodent …
unevenly. While studies of exploratory behavior have typically involved the laboratory rodent …
[HTML][HTML] Progressive impairment of directional and spatially precise trajectories by TgF344-Alzheimer's disease rats in the Morris Water Task
Spatial navigation is impaired in early stages of Alzheimer’s disease, and may be a defining
behavioral marker of preclinical AD. A new rat model (TgF344-AD) of AD overcomes many …
behavioral marker of preclinical AD. A new rat model (TgF344-AD) of AD overcomes many …
The effects of developmental alcohol exposure on the neurobiology of spatial processing
The consumption of alcohol during gestation is detrimental to the developing central nervous
system. One functional outcome of this exposure is impaired spatial processing, defined as …
system. One functional outcome of this exposure is impaired spatial processing, defined as …
[HTML][HTML] A comparison of neural decoding methods and population coding across thalamo-cortical head direction cells
Head direction (HD) cells, which fire action potentials whenever an animal points its head in
a particular direction, are thought to subserve the animal’s sense of spatial orientation. HD …
a particular direction, are thought to subserve the animal’s sense of spatial orientation. HD …
[PDF][PDF] Altered hippocampal place cell representation and theta rhythmicity following moderate prenatal alcohol exposure
Prenatal alcohol exposure (PAE) leads to profound deficits in spatial memory and synaptic
and cellular alterations to the hippocampus that last into adulthood. Neurons in the …
and cellular alterations to the hippocampus that last into adulthood. Neurons in the …
Prenatal alcohol exposure disrupts hippocampal sharp-wave ripple-associated spike dynamics
Prenatal alcohol exposure (PAE) is among the most common developmental insults to the
nervous system and is characterized by memory disruption. There is a pressing need to …
nervous system and is characterized by memory disruption. There is a pressing need to …
Impairment of the anterior thalamic head direction cell network following administration of the NMDA antagonist MK-801
Head direction (HD) cells, found in the rodent Papez circuit, are thought to form the neural
circuitry responsible for directional orientation. Because NMDA transmission has been …
circuitry responsible for directional orientation. Because NMDA transmission has been …
NMDA blockade inhibits experience-dependent modification of anterior thalamic head direction cells.
LE Berkowitz, I Ybarra, JA Jones, ME Amato… - Behavioral …, 2015 - psycnet.apa.org
Head Direction (HD) cells of the rodent Papez circuit are thought to reflect the spatial orientation
of the animal. Because NMDA transmission is important for spatial behavior, we sought …
of the animal. Because NMDA transmission is important for spatial behavior, we sought …