Bipolar disorder is a heritable mental illness with complex etiology. We performed a genome-wide
association study of 41,917 bipolar disorder cases and 371,549 controls of European …

Certain complex phenotypes appear repeatedly across diverse species due to processes of
evolutionary conservation and convergence. In some contexts like developmental body …

Causal genes and variants within genome-wide association study (GWAS) loci can be
identified by integrating GWAS statistics with expression quantitative trait loci (eQTL) and …

Host genetics is a key determinant of COVID-19 outcomes. Previously, the COVID-19 Host
Genetics Initiative genome-wide association study used common variants to identify multiple …

To reveal post-traumatic stress disorder (PTSD) genetic risk influences on tissue-specific gene
expression, we use brain and non-brain transcriptomic imputation. We impute genetically …

Agonistic encounters are powerful effectors of future behavior, and the ability to learn from
this type of social challenge is an essential adaptive trait. We recently identified a conserved …

Background Anorexia nervosa (AN) is a psychiatric disorder with complex etiology, with a
significant portion of disease risk imparted by genetics. Traditional genome-wide association …

Activity-dependent neuroprotective protein (ADNP) syndrome is a rare genetic condition
associated with intellectual disability and autism spectrum disorder. Preclinical evidence …

Obsessive-compulsive disorder (OCD) is a heritable disorder, but no definitive, replicated
OCD susceptibility loci have yet been identified by any genome-wide association study (GWAS…

Mice lacking HIP/RPL29, a ribosomal modulator of protein synthesis rate, display a short
stature phenotype. To understand the contribution of HIP/RPL29 to bone formation and adult …