The potential of the diverse chemistries present in natural products (NP) for biotechnology
and medicine remains untapped because NP databases are not searchable with raw data …

A major goal in natural product discovery programs is to rapidly dereplicate known entities
from complex biological extracts. We demonstrate here that molecular networking, an …

Despite rapid evolution in the area of microbial natural products chemistry, there is currently
no open access database containing all microbially produced natural product structures. …

Although mass spectrometry is a century old technology, we are entering into an exciting
time for the analysis of molecular information directly from complex biological systems. In this …

Genomics and metabolomics are widely used to explore specialized metabolite diversity.
The Paired Omics Data Platform is a community initiative to systematically document links …

Pseudomonads are cosmopolitan microorganisms able to produce a wide array of
specialized metabolites. These molecules allow Pseudomonas to scavenge nutrients, sense …

Ralstonia solanacearum is a globally distributed soil-borne plant pathogenic bacterium, which
shares a broad ecological range with many plant- and soil-associated fungi. We sought to …

Microorganisms such as bacteria and fungi produce a variety of specialized metabolites that
are invaluable for agriculture, biological research, and drug discovery. However, the …

Leishmaniasis is a debilitating disease caused by protozoan parasites of the genus
Leishmania, which affects an estimated 12 million people worldwide. The discovery of new lead …

Microbial interactions are expected to be major determinants of microbiome structure and
function. Although fungi are found in diverse microbiomes, their interactions with bacteria …