Pharmaceuticals represent a diverse collection of thousands of bioactive chemicals used in
human and veterinary medicine. The increased consumption, together with the recent …

Pancreatic ductal adenocarcinoma (PDAC) is characterized by the presence of abundant
desmoplastic stroma primarily composed of cancer-associated fibroblasts (CAFs). It is …

Five-year survival for pancreatic ductal adenocarcinoma (PDAC) patients remains below 7%
due to the lack of effective treatments. Here, we report that combined ablation of EGFR and …

Intestinal microfold cells (M cells) are a dynamic lineage of epithelial cells that initiate
mucosal immunity in the intestine. They are responsible for the uptake and transcytosis of …

Reports indicating the presence of pharmaceutical in fresh water environment in the ng L −1
to µg L −1 range are occurring with increasing frequency. It is also a fact that …

A battery of biomarkers was evaluated on Ruditapes philippinarum exposed during 14 days
to caffeine, ibuprofen, carbamazepine and novobiocin (0.1, 1, 5, 10, 15, and 50 µg L −1 ). …

Although pharmaceuticals have been detected in the environment only in the range from ng/L
to μg/L, it has been demonstrated that they can adversely affect the health status of aquatic …

Emerging contaminants (ECs) and regulated compounds (RCs) from three different WWTP
effluents were measured in the current study. The efficiency of two tertiary treatments, …

In the last few decades, there has been a growing interest in understanding the behavior of
personal care products (PCPs) in the aquatic environment. In this regard, the aim of this …

Two marine invertebrates, the crab Carcinus maenas and the clam Ruditapes philippinarum,
were used as bioindicator species to assess contamination when exposed in situ to …