Bacterial sphingomyelinases and phospholipases are a heterogeneous group of esterases
which are usually surface associated or secreted by a wide variety of Gram-positive and …

Phospholipases A 2 are a major component of snake venoms. Some of them cause severe
muscle necrosis through an unknown mechanism. Phospholipid hydrolysis is a possible …

Clostridium perfringens phospholipase C (CpPLC), also called α-toxin, is the most toxic
extracellular enzyme produced by this bacteria and is essential for virulence in gas gangrene. At …

SARS-CoV-2 receptor binding domain (RBD) recognizes the angiotensin converting enzyme
2 (ACE2) receptor in host cells that enables infection. Due to its antigenic specificity, RBD …

Bacterial phospholipases and sphingomyelinases are lipolytic esterases that are structurally
and evolutionarily heterogeneous. These enzymes play crucial roles as virulence factors in …

Phospholipases A 2 (PLA 2 s) and PLA 2 -like proteins are significant components of snake
venoms. Some of these proteins act as potent toxins causing muscle necrosis, which may …

Clostridium perfringens, the most broadly distributed pathogen in nature, produces a prototype
phospholipase C, also called α-toxin, which plays a key role in the pathogenesis of gas …

Clostridium perfringens phospholipase C ( CpPLC ), also called α‐toxin, plays a key role in
the pathogenesis of gas gangrene. CpPLC may lead to cell lysis at concentrations that cause …

Bacterial sphingomyelinases (SMases) and phospholipases (PLases) constitute a heterogeneous
group of esterases, surface-associated or secreted by a variety of Grampositive and …

Clostridium perfringens phospholipase C (CpPLC) plays a key role in the pathogenesis of
gas gangrene, an acute and life-threatening infection in humans. CpPLC leads to the …