Biological membranes define not only the cell boundaries but any compartment within the
cell. To some extent, the functionality of membranes is related to the elastic properties of the …

Phosphoinositides play a central role in many physiological processes by assisting the
recruitment of proteins to membranes through specific phosphoinositide-binding motifs. How this …

Atomic force microscopy (AFM) was developed in the 1980s following the invention of its
precursor, scanning tunneling microscopy (STM), earlier in the decade. Several modes of …

The erythrocyte membrane, a metabolically regulated active structure that comprises lipid
molecules, junctional complexes, and the spectrin network, enables the cell to undergo large …

10.7554/eLife.37262.001 One challenge in cell biology is to decipher the biophysical
mechanisms governing protein enrichment on curved membranes and the resulting membrane …

Clathrin-mediated endocytosis (CME) is a central trafficking pathway in eukaryotic cells
regulated by phosphoinositides. The plasma membrane phosphatidylinositol-4, 5-bisphosphate (…

Phosphoinositides are master regulators of multiple cellular processes: from vesicular
trafficking to signaling, cytoskeleton dynamics, and cell growth. They are synthesized by the …

Excitation-contraction coupling requires a highly specialized membrane structure, the triad,
composed of a plasma membrane invagination, the T-tubule, surrounded by two …

A double septin ring accompanies cytokinesis in yeasts and mammalian cells. In budding
yeast, reorganisation of the septin collar at the bud neck into a dynamic double ring is …

The capacity of proteins to function relies on a balance between molecular stability to
maintain their folded state and structural flexibility allowing conformational changes related to …