User profiles for Laura R. Botigue

Laura R Botigué

Centre for Research in Agricultural Genomics
Verified email at cragenomica.es
Cited by 3095

High-depth African genomes inform human migration and health

A Choudhury, S Aron, LR Botigué, D Sengupta… - Nature, 2020 - nature.com
The African continent is regarded as the cradle of modern humans and African genomes
contain more genetic variation than those from any other continent, yet only a fraction of the …

A universal probe set for targeted sequencing of 353 nuclear genes from any flowering plant designed using k-medoids clustering

MG Johnson, L Pokorny, S Dodsworth… - Systematic …, 2019 - academic.oup.com
Laura R Botigué , Laura R Botigué … Statistical analysis of sequence recovery was
conducted in R (Version 3.4.2, R Core Development Team, 2017). Sequence reads have been …

[HTML][HTML] Genomic ancestry of North Africans supports back-to-Africa migrations

BM Henn, LR Botigué, S Gravel, W Wang… - PLoS …, 2012 - journals.plos.org
North African populations are distinct from sub-Saharan Africans based on cultural, linguistic,
and phenotypic attributes; however, the time and the extent of genetic divergence between …

[HTML][HTML] Ancient European dog genomes reveal continuity since the Early Neolithic

LR Botigué, S Song, A Scheu, S Gopalan… - Nature …, 2017 - nature.com
Europe has played a major role in dog evolution, harbouring the oldest uncontested Palaeolithic
remains and having been the centre of modern dog breed creation. Here we sequence …

Estimating the mutation load in human genomes

BM Henn, LR Botigué, CD Bustamante… - Nature Reviews …, 2015 - nature.com
Next-generation sequencing technology has facilitated the discovery of millions of genetic
variants in human genomes. A sizeable fraction of these variants are predicted to be …

Distance from sub-Saharan Africa predicts mutational load in diverse human genomes

BM Henn, LR Botigué, S Peischl… - Proceedings of the …, 2016 - National Acad Sciences
The Out-of-Africa (OOA) dispersal ∼50,000 y ago is characterized by a series of founder
events as modern humans expanded into multiple continents. Population genetics theory …

A comprehensive phylogenomic platform for exploring the angiosperm tree of life

WJ Baker, P Bailey, V Barber, A Barker… - Systematic …, 2022 - academic.oup.com
Laura R Botigué , Laura R Botigué … (option -m GTR+F+R). The use of a single model
without testing many models of evolution was a pragmatic choice, following Abadi et al. (2019). …

Gene flow from North Africa contributes to differential human genetic diversity in southern Europe

LR Botigué, BM Henn, S Gravel… - Proceedings of the …, 2013 - National Acad Sciences
Human genetic diversity in southern Europe is higher than in other regions of the continent.
This difference has been attributed to postglacial expansions, the demic diffusion of …

[HTML][HTML] Genome-wide diversity in the levant reveals recent structuring by culture

M Haber, D Gauguier, S Youhanna, N Patterson… - PLoS …, 2013 - journals.plos.org
The Levant is a region in the Near East with an impressive record of continuous human
existence and major cultural developments since the Paleolithic period. Genetic and …

[HTML][HTML] North African populations carry the signature of admixture with Neandertals

F Sánchez-Quinto, LR Botigué, S Civit, C Arenas… - 2012 - journals.plos.org
One of the main findings derived from the analysis of the Neandertal genome was the
evidence for admixture between Neandertals and non-African modern humans. An alternative …