The Ebola virus disease epidemic in West Africa is the largest on record, responsible for over
28,599 cases and more than 11,299 deaths 1 . Genome sequencing in viral outbreaks is …

Background. National surveillance of gastrointestinal pathogens, such as Shiga toxin–producing
Escherichia coli O157 (STEC O157), is key to rapidly identifying linked cases in the …

Despite the magnitude of the Ebola virus disease (EVD) outbreak in West Africa, there is still
a fundamental lack of knowledge about the pathophysiology of EVD 1 . In particular, very …

Surveillance of drug-resistant bacteria is essential for healthcare providers to deliver
effective empirical antibiotic therapy. However, traditional molecular epidemiology does not …

In England in 2015, Shigella sonnei isolates from men who have sex with men produced
extended-spectrum β-lactamases and exhibited macrolide resistance. Whole-genome …

Background In 2015, the laboratory at the Ebola treatment center in Coyah, Guinea, confirmed
Ebola virus disease (EVD) in 286 patients. The cycle threshold (Ct) of an Ebola virus–…

Following a large outbreak of foodborne gastrointestinal (GI) disease, a multiplex PCR
approach was used retrospectively to investigate faecal specimens from 88 of the 413 reported …

Salmonella enterica serovar Enteritidis is one of the most frequent causes of Salmonellosis
globally and is commonly transmitted from animals to humans by the consumption of …

Background Human Ebola infection is characterized by a paralysis of the immune system. A
signature of αβ T cells in fatal Ebola infection has been recently proposed, while the …

Genomics, combined with population mobility data, used to map importation and spatial
spread of SARS-CoV-2 in high-income countries has enabled the implementation of local …