The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants
with mutations in key antibody epitopes has raised concerns that antigenic evolution could …

Rapid antigenic evolution enables the persistence of seasonal influenza A and B viruses in
human populations despite widespread herd immunity. Understanding viral mechanisms …

An effective vaccine is essential for controlling the spread of the SARS-CoV-2 virus. Here, we
describe an influenza virus-based vaccine for SARS-CoV-2. We incorporated a membrane-…

The emergence of SARS-CoV-2 variants with mutations in key antibody epitopes has raised
concerns that antigenic evolution will erode immunity. The susceptibility of immunity to viral …

A continuously growing immortal cell substrate can be used for virus propagation, diagnostic
purposes, and vaccine production. The aim of this study was to develop an immortal …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection elicits an antibody
response that targets several viral proteins including spike (S) and nucleocapsid (N); S is …

Influenza is one of the best-studied viruses of all time, and as such, it serves as a testbed to
extend our biological knowledge to the nanoscale. Many of the key processes underlying …

Influenza virus infection elicits antibodies against the receptor-binding protein hemagglutinin
(HA) and the receptor-cleaving protein neuraminidase (NA). Because HA is essential for …

… Gentles, Andrew J. Oler, Martina Kosikova, Matthew Angel, Javier G. Magadán, Hang Xie,
Christopher B. … Kosik I, Ince WL, Gentles LE, Oler AJ, Kosikova M, Angel M, et al. (2018) …

Primary cultured cells derived from normal tissue have a limited lifespan due to replicative
senescence and show distinct phenotypes such as irreversible cell cycle arrest and enlarged …