User profiles for Lauren E. Grosberg

Lauren E Grosberg

SRI International
Verified email at sri.com
Cited by 449

Activation of ganglion cells and axon bundles using epiretinal electrical stimulation

LE Grosberg, K Ganesan, GA Goetz… - Journal of …, 2017 - journals.physiology.org
Epiretinal prostheses for treating blindness activate axon bundles, causing large, arc-shaped
visual percepts that limit the quality of artificial vision. Improving the function of epiretinal …

Epiretinal stimulation with local returns enhances selectivity at cellular resolution

VH Fan, LE Grosberg, SS Madugula… - Journal of neural …, 2019 - iopscience.iop.org
Objective. Epiretinal prostheses are designed to restore vision in people blinded by photoreceptor
degenerative diseases, by directly activating retinal ganglion cells (RGCs) using an …

[HTML][HTML] Electrical stimulus artifact cancellation and neural spike detection on large multi-electrode arrays

GE Mena, LE Grosberg, S Madugula… - PLoS computational …, 2017 - journals.plos.org
Simultaneous electrical stimulation and recording using multi-electrode arrays can provide
a valuable technique for studying circuit connectivity and engineering neural interfaces. …

Calcium imaging of infrared-stimulated activity in rodent brain

…, MB Bouchard, MM Chernov, BR Chen, LE Grosberg… - Cell calcium, 2014 - Elsevier
Infrared neural stimulation (INS) is a promising neurostimulation technique that can activate
neural tissue with high spatial precision and without the need for exogenous agents. …

Spatially patterned bi-electrode epiretinal stimulation for axon avoidance at cellular resolution

RS Vilkhu, SS Madugula, LE Grosberg… - Journal of neural …, 2021 - iopscience.iop.org
Objective. Epiretinal prostheses are designed to restore vision to people blinded by photoreceptor
degenerative diseases by stimulating surviving retinal ganglion cells (RGCs), which …

[HTML][HTML] Spectral characterization and unmixing of intrinsic contrast in intact normal and diseased gastric tissues using hyperspectral two-photon microscopy

LE Grosberg, AJ Radosevich, S Asfaha, TC Wang… - PLoS one, 2011 - journals.plos.org
Background Living tissues contain a range of intrinsic fluorophores and sources of second
harmonic generation which provide contrast that can be exploited for fresh tissue imaging. …

High-fidelity reproduction of visual signals by electrical stimulation in the central primate retina

AR Gogliettino, SS Madugula, LE Grosberg… - Journal of …, 2023 - Soc Neuroscience
Electrical stimulation of retinal ganglion cells (RGCs) with electronic implants provides
rudimentary artificial vision to people blinded by retinal degeneration. However, current devices …

Inference of electrical stimulation sensitivity from recorded activity of primate retinal ganglion cells

…, R Vilkhu, NP Shah, LE Grosberg… - Journal of …, 2023 - Soc Neuroscience
High-fidelity electronic implants can in principle restore the function of neural circuits by
precisely activating neurons via extracellular stimulation. However, direct characterization of the …

[PDF][PDF] High-fidelity restoration of visual signals by electrical stimulation in the central primate retina

AR Gogliettino, SS Madugula, LE Grosberg, RS Vilkhu… - bioRxiv, 2022 - scholar.archive.org
Electrical stimulation of retinal ganglion cells (RGCs) with electronic implants provides
rudimentary artificial vision to people blinded by retinal degeneration, but cannot reproduce the …

Simultaneous multiplane in vivo nonlinear microscopy using spectral encoding

LE Grosberg, BR Chen, EMC Hillman - Optics letters, 2012 - opg.optica.org
Conventional point-by-point imaging schemes for laser scanning microscopy limit
acquisition speeds, particularly when imaging three-dimensional volumes. We report a novel …