Development and applications of a CRISPR activation system for facile genetic overexpression in Candida albicans
NC Gervais, AA La Bella, LF Wensing, J Sharma… - G3, 2023 - academic.oup.com
For the fungal pathogen Candida albicans, genetic overexpression readily occurs via a
diversity of genomic alterations, such as aneuploidy and gain-of-function mutations, with …
diversity of genomic alterations, such as aneuploidy and gain-of-function mutations, with …
A CRISPR Interference Platform for Efficient Genetic Repression in Candida albicans
L Wensing, J Sharma, D Uthayakumar, Y Proteau… - Msphere, 2019 - Am Soc Microbiol
Fungal pathogens are emerging as an important cause of human disease, and Candida
albicans is among the most common causative agents of fungal infections. Studying this fungal …
albicans is among the most common causative agents of fungal infections. Studying this fungal …
[HTML][HTML] CRISPR-Based Genetic Manipulation of Candida Species: Historical Perspectives and Current Approaches
D Uthayakumar, J Sharma, L Wensing… - Frontiers in Genome …, 2021 - frontiersin.org
The Candida genus encompasses a diverse group of ascomycete fungi that have captured
the attention of the scientific community, due to both their role in pathogenesis and emerging …
the attention of the scientific community, due to both their role in pathogenesis and emerging …
Design and Generation of a CRISPR Interference System for Genetic Repression and Essential Gene Analysis in the Fungal Pathogen Candida albicans
L Wensing, RS Shapiro - Essential Genes and Genomes: Methods and …, 2022 - Springer
Studying life-threatening fungal pathogens such as Candida albicans is of critical
importance, yet progress can be hindered by challenges associated with manipulating these …
importance, yet progress can be hindered by challenges associated with manipulating these …
The catheterized bladder environment promotes Efg1- and Als1-dependent Candida albicans infection
…, JJ Molina, A Molesan, PV Stuckey, L Wensing… - Science …, 2023 - science.org
Catheter-associated urinary tract infections (CAUTIs) account for 40% of hospital-acquired
infections (HAIs). As 20 to 50% of hospitalized patients receive catheters, CAUTIs are one of …
infections (HAIs). As 20 to 50% of hospitalized patients receive catheters, CAUTIs are one of …
[PDF][PDF] A CRISPR interference platform for efficient genetic repression in Candida albicans. mSphere 4: e00002-19
L Wensing, J Sharma, D Uthayakumar, Y Proteau… - 2019 - academia.edu
Fungal pathogens are emerging as an important cause of human disease, and Candida
albicans is among the most common causative agents of fungal infections. Studying this fungal …
albicans is among the most common causative agents of fungal infections. Studying this fungal …
Canola engineered with a microalgal polyketide synthase-like system produces oil enriched in docosahexaenoic acid
…, LM Clark, W Chen, PS Adu-Peasah, ST Wensing… - Nature …, 2016 - nature.com
Dietary omega-3 long-chain polyunsaturated fatty acids (LC-PUFAs), docosahexaenoic acid
(DHA, C22:6) and eicosapentaenoic acid (EPA, C20:5) are usually derived from marine fish…
(DHA, C22:6) and eicosapentaenoic acid (EPA, C20:5) are usually derived from marine fish…
Facilitators and barriers to implementation of safe infant sleep recommendations in the hospital setting
ER Colson, P Schaeffer, FR Hauck, L Provini… - Journal of Obstetric …, 2019 - Elsevier
… We identified themes and subthemes, and the taxonomy fit into the Grol and Wensing
framework for change in clinical practice. The six primary themes included The Innovation Itself, …
framework for change in clinical practice. The six primary themes included The Innovation Itself, …
Global dispersal pattern of HIV type 1 subtype CRF01_AE: a genetic trace of human mobility related to heterosexual sexual activities centralized in Southeast Asia
…, D Struck, J Vercauteren, AMJ Wensing… - The Journal of …, 2015 - academic.oup.com
Background. Human immunodeficiency virus type 1 (HIV-1) subtype CRF01_AE originated
in Africa and then passed to Thailand, where it established a major epidemic. Despite the …
in Africa and then passed to Thailand, where it established a major epidemic. Despite the …
Pharmacokinetic interaction study between riociguat and the combined oral contraceptives levonorgestrel and ethinylestradiol in healthy postmenopausal women
…, C Becker, S Saleh, G Wensing… - Pulmonary …, 2016 - journals.sagepub.com
Female patients requiring treatment for pulmonary arterial hypertension (PAH) are advised to
avoid pregnancy because of the high associated mortality rate. Oral contraception is one of …
avoid pregnancy because of the high associated mortality rate. Oral contraception is one of …