African swine fever virus Georgia isolate harboring deletions of MGF360 and MGF505 genes is attenuated in swine and confers protection against challenge with …
V O'Donnell, LG Holinka, DP Gladue, B Sanford… - Journal of …, 2015 - Am Soc Microbiol
African swine fever virus (ASFV) is the etiological agent of a contagious and often lethal disease
of domestic pigs that has significant economic consequences for the swine industry. The …
of domestic pigs that has significant economic consequences for the swine industry. The …
Development of a highly effective African swine fever virus vaccine by deletion of the I177L gene results in sterile immunity against the current epidemic Eurasia strain
African swine fever virus (ASFV) is the etiological agent of a contagious and often lethal disease
of domestic pigs that has significant economic consequences for the swine industry. The …
of domestic pigs that has significant economic consequences for the swine industry. The …
Simultaneous Deletion of the 9GL and UK Genes from the African Swine Fever Virus Georgia 2007 Isolate Offers Increased Safety and Protection against …
V O'Donnell, GR Risatti, LG Holinka, PW Krug… - Journal of …, 2017 - Am Soc Microbiol
African swine fever virus (ASFV) is the etiological agent of a contagious and often lethal viral
disease of domestic pigs that has significant economic consequences for the swine industry…
disease of domestic pigs that has significant economic consequences for the swine industry…
African Swine Fever Virus Georgia 2007 with a Deletion of Virulence-Associated Gene 9GL (B119L), when Administered at Low Doses, Leads to Virus Attenuation in …
African swine fever virus (ASFV) is the etiological agent of an often lethal disease of domestic
pigs. Disease control strategies have been hampered by the unavailability of vaccines …
pigs. Disease control strategies have been hampered by the unavailability of vaccines …
The progressive adaptation of a georgian isolate of African swine fever virus to vero cells leads to a gradual attenuation of virulence in swine corresponding to major …
PW Krug, LG Holinka, V O'Donnell, B Reese… - Journal of …, 2015 - Am Soc Microbiol
African swine fever virus (ASFV) causes a contagious and often lethal disease of feral and
domestic swine. Experimental vaccines derived from naturally occurring, genetically modified, …
domestic swine. Experimental vaccines derived from naturally occurring, genetically modified, …
African swine fever virus Georgia isolate harboring deletions of 9GL and MGF360/505 genes is highly attenuated in swine but does not confer protection against …
V O'Donnell, LG Holinka, B Sanford, PW Krug… - Virus research, 2016 - Elsevier
African swine fever virus (ASFV) produces a contagious disease of domestic pigs that results
in severe economic consequences to the swine industry. Control of the disease has been …
in severe economic consequences to the swine industry. Control of the disease has been …
[HTML][HTML] Deletion of CD2-like gene from the genome of African swine fever virus strain Georgia does not attenuate virulence in swine
MV Borca, V o'Donnell, LG Holinka, GR Risatti… - Scientific reports, 2020 - nature.com
The CD2-like African swine fever virus (ASFV) gene 8DR, (also known as EP402R)
encodes for a structural transmembrane glycoprotein that has been shown to mediate …
encodes for a structural transmembrane glycoprotein that has been shown to mediate …
[HTML][HTML] CRISPR-Cas9, a tool to efficiently increase the development of recombinant African swine fever viruses
African swine fever virus (ASFV) causes a highly contagious disease called African swine
fever. This disease is often lethal for domestic pigs, causing extensive losses for the swine …
fever. This disease is often lethal for domestic pigs, causing extensive losses for the swine …
[HTML][HTML] Association of the host immune response with protection using a live attenuated African swine fever virus model
…, M Alfano, L Velazquez Salinas, LG Holinka… - Viruses, 2016 - mdpi.com
African swine fever (ASF) is a lethal hemorrhagic disease of swine caused by a double-stranded
DNA virus, ASF virus (ASFV). There is no vaccine to prevent the disease and current …
DNA virus, ASF virus (ASFV). There is no vaccine to prevent the disease and current …
Classical swine fever virus p7 protein is a viroporin involved in virulence in swine
DP Gladue, LG Holinka, E Largo… - Journal of …, 2012 - Am Soc Microbiol
The nonstructural protein p7 of classical swine fever virus (CSFV) is a small hydrophobic
polypeptide with an apparent molecular mass of 6 to 7 kDa. The protein contains two …
polypeptide with an apparent molecular mass of 6 to 7 kDa. The protein contains two …