Engineering Promoter Architecture in Oleaginous Yeast Yarrowia lipolytica
M Shabbir Hussain, L Gambill, S Smith… - ACS synthetic …, 2016 - ACS Publications
Eukaryotic promoters have a complex architecture to control both the strength and timing of
gene transcription spanning up to thousands of bases from the initiation site. This complexity …
gene transcription spanning up to thousands of bases from the initiation site. This complexity …
Optogenetic control of gut bacterial metabolism to promote longevity
Gut microbial metabolism is associated with host longevity. However, because it requires
direct manipulation of microbial metabolism in situ, establishing a causal link between these …
direct manipulation of microbial metabolism in situ, establishing a causal link between these …
[HTML][HTML] Recent advances in bioengineering of the oleaginous yeast Yarrowia lipolytica
The oleaginous yeast, Yarrowia lipolytica, is becoming increasing popular for metabolic
engineering applications. Advances in synthetic biology and metabolic engineering have …
engineering applications. Advances in synthetic biology and metabolic engineering have …
[HTML][HTML] Engineering xylose utilization in Yarrowia lipolytica by understanding its cryptic xylose pathway
Background The oleaginous yeast, Yarrowia lipolytica, has been utilized as an industrial host
for about 60 years for various applications. Recently, the metabolic engineering of this host …
for about 60 years for various applications. Recently, the metabolic engineering of this host …
[HTML][HTML] Alternative substrate metabolism in Yarrowia lipolytica
M Spagnuolo, M Shabbir Hussain, L Gambill… - Frontiers in …, 2018 - frontiersin.org
Recent advances in genetic engineering capabilities have enabled the development of
oleochemical producing strains of Yarrowia lipolytica. Much of the metabolic engineering effort …
oleochemical producing strains of Yarrowia lipolytica. Much of the metabolic engineering effort …
Changing who has a seat and voice at the table: how the Academic Pediatric Association is responding to systemic racism
…, C Orr, J Konrath, U Oddiri, CJ Russell, L Gambill… - Academic …, 2022 - Elsevier
The Academic Pediatrics Association has taken multiple steps over the last 2 years to
incorporate the lenses of anti-racism and social justice into our mission and work. In this …
incorporate the lenses of anti-racism and social justice into our mission and work. In this …
[HTML][HTML] A split ribozyme that links detection of a native RNA to orthogonal protein outputs
Individual RNA remains a challenging signal to synthetically transduce into different types of
cellular information. Here, we describe Ribozyme-ENabled Detection of RNA (RENDR), a …
cellular information. Here, we describe Ribozyme-ENabled Detection of RNA (RENDR), a …
Brave new 'RNA'world—advances in RNA tools and their application for understanding and engineering biological systems
Our ability to program how cells express their genetic material is central to our ability to
understand and engineer them. While a range of biomolecules can be used to control gene …
understand and engineer them. While a range of biomolecules can be used to control gene …
Information storage across a microbial community using universal RNA memory
Biological recorders can code information in DNA, but they remain challenging to apply in
complex microbial communities. To program microbiome information storage, a synthetic …
complex microbial communities. To program microbiome information storage, a synthetic …
[HTML][HTML] Demystifying the Op-Ed. A novel group writing workshop to improve upon existing pediatric advocacy training
LC van der List, D Blumberg, STT Li, L Gambill - Academic Pediatrics, 2022 - Elsevier
What's New An op-ed writing workshop utilizing a group compilation exercise increases
participant self-reported comfort in writing op-eds and has led to published op-eds. An …
participant self-reported comfort in writing op-eds and has led to published op-eds. An …