During the implantation window, the endometrium becomes poised to transition to a
pregnant state, a process driven by differentiation of stromal cells into decidual cells (DC). …

Recurrent pregnancy loss (RPL), defined as multiple consecutive miscarriages, is a devastating
disorder for which there are no good treatment options. Two opposing paradigms have …

Background Recurrent pregnancy loss (RPL) is associated with the loss of endometrial
mesenchymal stem-like progenitor cells (eMSC). DPP4 inhibitors may increase homing and …

In pregnancy, resistance of endometrial decidual cells to stress signals is critical for the
integrity of the fetomaternal interface and, by extension, survival of the conceptus. O-…

Background Studies have shown an association between recurrent miscarriage and inherited
thrombophilia. It has been hypothesized that anticoagulant therapy might reduce both …

Objectives Many women will seek information online about induction of labour. However,
the quality of the available information varies greatly and there are no regulations regarding …

Investigator-initiated studies are invaluable, especially in fields that are not particularly of
interest for the pharmaceutical industry because they are either less profitable or concern …

Objectives Macrosomic and large for gestational age (LGA) fetuses are at increased risk of
shoulder dystocia and associated complications. The aim of this thesis was to explore the …

Introduction Large-for-gestational age (LGA) fetuses have an increased risk of shoulder
dystocia. This can lead to adverse neonatal outcomes and death. Early induction of labour in …

Full dilatation caesarean sections (CS) have increased risk of uterine extensions, which leads
to cervical trauma that has been associated with an increased risk of spontaneous preterm …