[HTML][HTML] Cone-like morphological, molecular, and electrophysiological features of the photoreceptors of the Nrl knockout mouse
LL Daniele, C Lillo, AL Lyubarsky… - … & visual science, 2005 - iovs.arvojournals.org
… Photoreceptor responses (measured with the paired-flash method) of human ESCS patients’
S-cones were found to recover much more slowly than those of L/M-cones, and postmortem …
S-cones were found to recover much more slowly than those of L/M-cones, and postmortem …
[HTML][HTML] From candelas to photoisomerizations in the mouse eye by rhodopsin bleaching in situ and the light-rearing dependence of the major components of the …
AL Lyubarsky, LL Daniele, EN Pugh Jr - Vision research, 2004 - Elsevier
To quantify the rate at which light in a ganzfeld produces photoisomerizations in mouse rods
in situ, we measured the rate of rhodopsin bleaching in eyes of recently euthanized mice …
in situ, we measured the rate of rhodopsin bleaching in eyes of recently euthanized mice …
Photoreceptors of Nrl −/− Mice Coexpress Functional S- and M-cone Opsins Having Distinct Inactivation Mechanisms
SS Nikonov, LL Daniele, X Zhu, CM Craft… - The Journal of general …, 2005 - rupress.org
The retinas of mice null for the neural retina leucine zipper transcription factor (Nrl −/ − )
contain no rods but are populated instead with photoreceptors that on ultrastructural, …
contain no rods but are populated instead with photoreceptors that on ultrastructural, …
[PDF][PDF] Loss of the metalloprotease ADAM9 leads to cone-rod dystrophy in humans and retinal degeneration in mice
Cone-rod dystrophy (CRD) is an inherited progressive retinal dystrophy affecting the function
of cone and rod photoreceptors. By autozygosity mapping, we identified null mutations in …
of cone and rod photoreceptors. By autozygosity mapping, we identified null mutations in …
Altered visual function in monocarboxylate transporter 3 (Slc16a8) knockout mice
LL Daniele, B Sauer, SM Gallagher… - … of Physiology-Cell …, 2008 - journals.physiology.org
To meet the high-energy demands of photoreceptor cells, the outer retina metabolizes glucose
through glycolytic and oxidative pathways, resulting in large-scale production of lactate …
through glycolytic and oxidative pathways, resulting in large-scale production of lactate …
Novel distribution of junctional adhesion molecule‐C in the neural retina and retinal pigment epithelium
LL Daniele, RH Adams, DE Durante… - Journal of …, 2007 - Wiley Online Library
Junction adhesion molecules-A,-B, and-C (Jams) are cell surface glycoproteins that have
been shown to play an important role in the assembly and maintenance of tight junctions and …
been shown to play an important role in the assembly and maintenance of tight junctions and …
Mole Quantity of RPE65 and Its Productivity in the Generation of 11-cis-Retinal from Retinyl Esters in the Living Mouse Eye
…, AB Savchenko, SB Morocco, LL Daniele… - Biochemistry, 2005 - ACS Publications
RPE65, a protein expressed in cells of the retinal pigment epithelium of the eye, is essential
for the synthesis by isomerohydrolase of 11-cis-retinal, the chromophore of rod and cone …
for the synthesis by isomerohydrolase of 11-cis-retinal, the chromophore of rod and cone …
[HTML][HTML] Microtubule-associated protein 1 light chain 3B,(LC3B) is necessary to maintain lipid-mediated homeostasis in the retinal pigment epithelium
A Dhingra, BA Bell, NS Peachey, LL Daniele… - Frontiers in cellular …, 2018 - frontiersin.org
Like other neurons, retinal cells utilize autophagic pathways to maintain cell homeostasis.
The mammalian retina relies on heterophagy and selective autophagy to efficiently degrade …
The mammalian retina relies on heterophagy and selective autophagy to efficiently degrade …
[HTML][HTML] A mouse M-opsin monochromat: retinal cone photoreceptors have increased M-opsin expression when S-opsin is knocked out
LL Daniele, C Insinna, R Chance, J Wang, SS Nikonov… - Vision research, 2011 - Elsevier
Mouse cone photoreceptors, like those of most mammals including humans, express cone
opsins derived from two ancient families: S-opsin (gene Opn1sw) and M-opsin (gene Opn1mw…
opsins derived from two ancient families: S-opsin (gene Opn1sw) and M-opsin (gene Opn1mw…
[HTML][HTML] Glucose uptake by GLUT1 in photoreceptors is essential for outer segment renewal and rod photoreceptor survival
LL Daniele, JYS Han, IS Samuels… - … : official publication of …, 2022 - ncbi.nlm.nih.gov
Photoreceptors consume glucose supplied by the choriocapillaris to support phototransduction
and outer segment (OS) renewal. Reduced glucose supply underlies photoreceptor cell …
and outer segment (OS) renewal. Reduced glucose supply underlies photoreceptor cell …