Recent scientific advances have significantly contributed to our understanding of the complex
connection between the microbiome and cancer. Our bodies are continuously exposed to …

Advances in DNA sequencing technology have facilitated the determination of hundreds of
complete genome sequences both for bacteria and their bacteriophages. Some of these …

Genetic switches are critical components of developmental circuits. Because temperate
bacteriophages are vastly abundant and greatly diverse, they are rich resources for …

Enterovirus D68 (EV-D68) has historically been associated with respiratory illnesses. However,
in the summers of 2014 and 2016, EV-D68 outbreaks coincided with a spike in polio-like …

Here, we present a transformational approach to genome engineering of herpes simplex
virus type 1 (HSV-1), which has a large DNA genome, using synthetic genomics tools. We …

The delivery of large DNA vectors (>100 000 bp) remains a limiting step in the engineering
of mammalian cells and the development of human artificial chromosomes (HACs). Yeast is …

The recent emergence of Zika virus (ZIKV) has been concentrated in the Caribbean, Southeastern
United States, and South- and Central America; resulting in travel-based cases being …

Zika Virus (ZIKV) is a mosquito-borne flavivirus that the World Health Organization (WHO)
declared a global concern due to the severity of infection. This study focuses on determining …

Temperate bacteriophages express transcription repressors that maintain lysogeny by down-regulating
lytic promoters and confer superinfection immunity. Repressor regulation is …

Staphylococcus aureus is an opportunistic pathogen that causes a wide range of infections
and food poisoning in humans with antibiotic resistance, specifically to methicillin, …