In this FlyBook chapter, we present a survey of the current literature on the development of
the hematopoietic system in Drosophila. The Drosophila blood system consists entirely of …

Fluorescent derivatives of actin and actin-binding domains are powerful tools for studying
actin filament architecture and dynamics in live cells. Growing evidence, however, indicates …

Tropomyosins are coiled-coil proteins that bind actin filaments and regulate multiple
cytoskeletal functions, including actin network dynamics near the leading edge of motile cells. …

Mechanistic studies of Drosophila lymph gland hematopoiesis are limited by the availability
of cell-type-specific markers. Using a combination of bulk RNA-Seq of FACS-sorted cells, …

Most eukaryotic cells express multiple isoforms of the actin-binding protein tropomyosin that
help construct a variety of cytoskeletal networks. Only one nonmuscle tropomyosin (Tm1A) …

Dysregulated Notch signaling is a common feature of cancer; however, its effects on tumor
initiation and progression are highly variable, with Notch having either oncogenic or tumor-…

Genetic and genomic analysis in Drosophila suggests that hematopoietic progenitors likely
transition into terminal fates via intermediate progenitors (IPs) with some characteristics of …

During homeostasis, a critical balance is maintained between myeloid-like progenitors and
their differentiated progeny, which function to mitigate stress and innate immune challenges. …

Female friendships are significant to many Black females because they represent a homeplace,
or a safe space. This study uses Baxter and Montgomery's ( 1996 , 1998 ) relational …

Tropomyosin (TM) is an actin binding protein that has been implicated in a variety of
developmental and biological processes including neuronal morphogenesis, cell transformation, …