[PDF][PDF] Immune-instructive polymers control macrophage phenotype and modulate the foreign body response in vivo

HM Rostam, LE Fisher, AL Hook, L Burroughs… - Matter, 2020 - cell.com
Implanted medical devices often elicit adverse foreign body responses whereby macrophages
play a central role. Here, we identify simple polymers that instruct different immunological …

Discovery of a polymer resistant to bacterial biofilm, swarming, and encrustation

…, CA Lewis-Lloyd, JC Luckett, L Burroughs… - Science …, 2023 - science.org
Innovative approaches to prevent catheter-associated urinary tract infections (CAUTIs) are
urgently required. Here, we describe the discovery of an acrylate copolymer capable of …

Low-cost and sustainable organic thermoelectrics based on low-dimensional molecular metals

…, K Kostova, L Burroughs… - Advanced …, 2017 - nottingham-repository.worktribe.com
More than 70 % of the primary energy consumed world-wide is wasted, mostly as heat below
100 C[1]. Thermoelectric generators may convert a substantial amount of this energy into …

Discovery of (meth) acrylate polymers that resist colonization by fungi associated with pathogenesis and biodeterioration

…, VC Crucitti, G Figueredo, CR Davies, L Burroughs… - Science …, 2020 - science.org
Fungi have major, negative socioeconomic impacts, but control with bioactive agents is
increasingly restricted, while resistance is growing. Here, we describe an alternative fungal …

[HTML][HTML] Discovery of synergistic material-topography combinations to achieve immunomodulatory osteoinductive biomaterials using a novel in vitro screening method …

L Burroughs, MH Amer, M Vassey, B Koch… - Biomaterials, 2021 - Elsevier
Human mesenchymal stem cells (hMSCs) are widely represented in regenerative medicine
clinical strategies due to their compatibility with autologous implantation. Effective bone …

Multifunctional bioinstructive 3D architectures to modulate cellular behavior

…, L Jiang, J Thorpe, L Burroughs… - Advanced Functional …, 2019 - Wiley Online Library
Biological structures control cell behavior via physical, chemical, electrical, and mechanical
cues. Approaches that allow us to build devices that mimic these cues in a combinatorial …

[HTML][HTML] Development of dual anti-biofilm and anti-bacterial medical devices

L Burroughs, W Ashraf, S Singh… - Biomaterials …, 2020 - pubs.rsc.org
The rising occurrence of antimicrobial resistance demands new strategies for delivering
antibiotics to ensure their effective use. In this study, a multi-functional strategy to address …

Polymer microparticles with defined surface chemistry and topography mediate the formation of stem cell aggregates and cardiomyocyte function

…, J Thorpe, L Burroughs… - … applied materials & …, 2019 - ACS Publications
Surface-functionalized microparticles are relevant to fields spanning engineering and
biomedicine, with uses ranging from cell culture to advanced cell delivery. Varying topographies of …

Efficient asymmetric organocatalytic formation of erythrose and threose under aqueous conditions

L Burroughs, ME Vale, JAR Gilks, H Forintos… - Chemical …, 2010 - pubs.rsc.org
Esters of proteinogenic amino acids efficiently catalyse the formation of erythrose and
threose under aqueous conditions in the highest yields and enantioselectivities yet reported. …

Asymmetric organocatalytic formation of protected and unprotected tetroses under potentially prebiotic conditions

L Burroughs, PA Clarke, H Forintos… - Organic & …, 2012 - pubs.rsc.org
Esters of proteinogenic amino acids efficiently catalyse the formation of erythrose and threose
under potentially prebiotic conditions in the highest yields and enantioselectivities yet …