A standardized ontology for naming tRNA-derived RNAs based on molecular origin

AD Holmes, PP Chan, Q Chen, P Ivanov, L Drouard… - Nature …, 2023 - nature.com
Transfer RNA (tRNA), well-studied as the key adaptor molecule in protein translation, is now
known to be processed into a large collection of smaller stable RNAs. High-throughput small…

[HTML][HTML] How to build a ribosome from RNA fragments in Chlamydomonas mitochondria

…, F Förster, BD Engel, P Giegé, L Drouard… - Nature …, 2021 - nature.com
Mitochondria are the powerhouse of eukaryotic cells. They possess their own gene
expression machineries where highly divergent and specialized ribosomes, named hereafter …

[HTML][HTML] Complete Sequence, Multichromosomal Architecture and Transcriptome Analysis of the Solanum tuberosum Mitochondrial Genome

…, C Cantarella, E Ubrig, T Cardi, L Drouard… - International Journal of …, 2019 - mdpi.com
Mitochondrial genomes (mitogenomes) in higher plants can induce cytoplasmic male sterility
and be somehow involved in nuclear-cytoplasmic interactions affecting plant growth and …

High-dose mitotane strategy in adrenocortical carcinoma: prospective analysis of plasma mitotane measurement during the first 3 months of follow-up

…, A Al Ghuzlan, D Deandreis, L Drouard… - European journal of …, 2012 - academic.oup.com
Background The benefit-to-risk ratio of a high-dose strategy at the initiation of mitotane
treatment of adrenocortical carcinoma (ACC) remains unknown. Methods To evaluate the …

Arabidopsis tRNA-derived fragments as potential modulators of translation

S Lalande, R Merret, T Salinas-Giegé, L Drouard - RNA biology, 2020 - Taylor & Francis
Transfer RNA-derived fragments (tRFs) exist in all branches of life. They are involved in
RNA degradation, regulation of gene expression, ribosome biogenesis. In archaebacteria, …

The structure of the mouse ADAT2/ADAT3 complex reveals the molecular basis for mammalian tRNA wobble adenosine-to-inosine deamination

…, P Wolff, E Troesch, E Ennifar, L Drouard… - Nucleic Acids …, 2021 - academic.oup.com
Post-transcriptional modification of tRNA wobble adenosine into inosine is crucial for
decoding multiple mRNA codons by a single tRNA. The eukaryotic wobble adenosine-to-inosine …

The decoupled evolution of the organellar genomes of Silene nutans leads to distinct roles in the speciation process

…, C Godé, E Schmitt, S Mangenot, L Drouard… - New …, 2023 - Wiley Online Library
There is growing evidence that cytonuclear incompatibilities (ie disruption of cytonuclear
coadaptation) might contribute to the speciation process. In a former study, we described the …

Combining tRNA sequencing methods to characterize plant tRNA expression and post-transcriptional modification

…, NL Coots, JM Svendsen, KC Brown, L Drouard… - RNA biology, 2021 - Taylor & Francis
Differences in tRNA expression have been implicated in a remarkable number of biological
processes. There is growing evidence that tRNA genes can play dramatically different roles …

Plant tRNA functions beyond their major role in translation

M Chery, L Drouard - Journal of Experimental Botany, 2023 - academic.oup.com
Transfer RNAs (tRNAs) are well known for their essential function as adapters in delivering
amino acids to ribosomes and making the link between mRNA and protein according to the …

Rapid shifts in mitochondrial tRNA import in a plant lineage with extensive mitochondrial tRNA gene loss

…, DA Triant, DR Taylor, L Drouard… - Molecular Biology …, 2021 - academic.oup.com
In most eukaryotes, transfer RNAs (tRNAs) are one of the very few classes of genes remaining
in the mitochondrial genome, but some mitochondria have lost these vestiges of their …