N-methyl-d-aspartate receptors (NMDARs) are located in neuronal cell membranes at
synaptic and extrasynaptic locations, where they are believed to mediate distinct physiological …

The basis for differences in activity-dependent trafficking of AMPA receptors (AMPARs) and
NMDA receptors (NMDARs) remains unclear. Using single-molecule tracking, we found …

The identification of circulating autoantibodies against neuronal receptors in neuropsychiatric
disorders has fostered new conceptual and clinical frameworks. However, detection …

BACKGROUND Since it was established that the cognitive brain is formed mostly by an
interconnected network of neurons that communicate at contact sites termed synapses, intense …

Involuntary movements, or dyskinesia, represent a debilitating complication of levodopa (L-dopa)
therapy for Parkinson's disease (PD). L-dopa-induced dyskinesia (LID) are ultimately …

There is increasing recognition in the neurological and psychiatric literature of patients with
so-called isolated psychotic presentations (ie, with no, or minimal, neurological features) …

Synaptic activity regulates the postsynaptic accumulation of AMPA receptors over timescales
ranging from minutes to days. Indeed, the regulated trafficking and mobility of GluR1 AMPA …

Control of the glutamate time course in the synapse is crucial for excitatory transmission. This
process is mainly ensured by astrocytic transporters, high expression of which is essential …

During postnatal development, changes in the subunit composition of glutamate receptors of
the NMDA subtype (NMDARs) are key to the refinement of excitatory synapses. Hypotheses …

The cellular traffic of neurotransmitter receptors has captured a lot of attention over the last
decade, mostly because synaptic receptor number is adjusted during synaptic development …