The absorption, metabolism, and excretion of ibrutinib were investigated in healthy men
after administration of a single oral dose of 140 mg of 14 C-labeled ibrutinib. The mean (SD) …

With the recent publication of the FDA guidance on metabolites in safety testing (MIST), a
reflection is provided that describes the impact of this guidance on the processes of drug …

Messenger RNA vaccines have come into the spotlight as a promising and adaptive alternative
to conventional vaccine approaches. The efficacy of mRNA vaccines relies on the ability …

Material suitability needs to be considered for the 3D printing of solid oral dosage forms (SODFs).
This work aims to assess the suitability of a CO 2 laser (λ = 10.6 μm) for selective laser …

This work firstly aimed to synthesize mono- and di- sulfonic derivatives of chitosan by
reductive amination reaction using respectively 2-formyl benzene sulfonic acid and 2,4 formyl …

The improvement of separation efficiency for protein analysis in capillary electrophoresis (CE)
is a challenging topic in which protein adsorption onto the capillary wall plays a crucial role…

The aim of this work was to develop the formation of multilayered coating incorporating a
cyclodextrin polyelectrolyte onto a non-woven polyethylene terephthalate (PET) textile support …

Taylor dispersion analysis (TDA) is an absolute method (no calibration needed) for the
determination of the molecular diffusion coefficient (D) based on the band broadening of a solute …

Successive multiple ionic-polymer layers (SMIL) coatings have been often used in capillary
electrophoresis due to their simplicity to implement and regenerate. However, the …

Hemoglobin (Hb) constitutes an important protein in clinical diagnostics—both in humans and
animals. Among the high number of sequence variants, some can cause severe diseases. …