Episodes de mortalité massive de moules bleues observés en 2014 dans les Pertuis charentais
…, P Haffner, C Dubreuil, N Faury, L Baillon… - Bulletin …, 2015 - hal.science
Des épisodes de mortalité massive (90-100 %) ont été observés au sein des élevages de
moules touchant à la fois les animaux adultes et les juvéniles au printemps 2014, dans les …
moules touchant à la fois les animaux adultes et les juvéniles au printemps 2014, dans les …
[HTML][HTML] The furin cleavage site in the SARS-CoV-2 spike protein is required for transmission in ferrets
SARS-CoV-2 entry requires sequential cleavage of the spike glycoprotein at the S1/S2 and
the S2ʹ cleavage sites to mediate membrane fusion. SARS-CoV-2 has a polybasic insertion (…
the S2ʹ cleavage sites to mediate membrane fusion. SARS-CoV-2 has a polybasic insertion (…
[HTML][HTML] Histopathological findings and viral tropism in UK patients with severe fatal COVID-19: a post-mortem study
…, A Abdolrasouli, OC Swann, L Baillon… - The Lancet …, 2020 - thelancet.com
Background Severe COVID-19 has a high mortality rate. Comprehensive pathological
descriptions of COVID-19 are scarce and limited in scope. We aimed to describe the …
descriptions of COVID-19 are scarce and limited in scope. We aimed to describe the …
[HTML][HTML] Transcriptional reprogramming from innate immune functions to a pro-thrombotic signature by monocytes in COVID-19
…, EM Jones, MMH Tan, RC Saputil, L Baillon… - Nature …, 2022 - nature.com
Although alterations in myeloid cells have been observed in COVID-19, the specific underlying
mechanisms are not completely understood. Here, we examine the function of classical …
mechanisms are not completely understood. Here, we examine the function of classical …
Increased transmission of SARS-CoV-2 lineage B. 1.1. 7 (VOC 2020212/01) is not accounted for by a replicative advantage in primary airway cells or antibody escape
…, TP Peacock, R Frise, N Goonawardane, L Baillon… - BioRxiv, 2021 - biorxiv.org
Lineage B.1.1.7 (Variant of Concern 202012/01) is a new SARS-CoV-2 variant which was
first sequenced in the UK in September 2020 before becoming the majority strain in the UK …
first sequenced in the UK in September 2020 before becoming the majority strain in the UK …
The furin cleavage site of SARS-CoV-2 spike protein is a key determinant for transmission due to enhanced replication in airway cells
TP Peacock, DH Goldhill, J Zhou, L Baillon, R Frise… - BioRxiv, 2020 - biorxiv.org
SARS-CoV-2 enters cells via its spike glycoprotein which must be cleaved sequentially at the
S1/S2, then the S2’ cleavage sites (CS) to mediate membrane fusion. SARS-CoV-2 has a …
S1/S2, then the S2’ cleavage sites (CS) to mediate membrane fusion. SARS-CoV-2 has a …
[PDF][PDF] Mutations that adapt SARS-CoV-2 to mink or ferret do not increase fitness in the human airway
…, WT Harvey, R Kugathasan, R Frise, L Baillon… - Cell Reports, 2022 - cell.com
SARS-CoV-2 has a broad mammalian species tropism infecting humans, cats, dogs, and
farmed mink. Since the start of the 2019 pandemic, several reverse zoonotic outbreaks of SARS…
farmed mink. Since the start of the 2019 pandemic, several reverse zoonotic outbreaks of SARS…
[HTML][HTML] Distinct airway epithelial immune responses after infection with SARS-CoV-2 compared to H1N1
H Stölting, L Baillon, R Frise, K Bonner, RJ Hewitt… - Mucosal …, 2022 - Elsevier
Children are less likely than adults to suffer severe symptoms when infected with severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), while influenza A H1N1 severity is …
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), while influenza A H1N1 severity is …
[HTML][HTML] Ostreid herpesvirus type 1 replication and host response in adult Pacific oysters, Crassostrea gigas
A Segarra, L Baillon, D Tourbiez, A Benabdelmouna… - Veterinary …, 2014 - Springer
Since 2008, massive mortality outbreaks associated with OsHV-1 detection have been reported
in Crassostrea gigas spat and juveniles in several countries. Nevertheless, adult oysters …
in Crassostrea gigas spat and juveniles in several countries. Nevertheless, adult oysters …
[HTML][HTML] An Influenza A virus can evolve to use human ANP32E through altering polymerase dimerization
…, R Penn, OK Platt, K Sukhova, L Baillon… - Nature …, 2023 - nature.com
Human ANP32A and ANP32B are essential but redundant host factors for influenza virus
genome replication. While most influenza viruses cannot replicate in edited human cells …
genome replication. While most influenza viruses cannot replicate in edited human cells …