User profiles for Lautaro Belifori

Lautaro F. Belfiori-Carrasco

Nordic Bioscience, Herlev, Denmark
Verified email at nordicbio.com
Cited by 53

Endoplasmic reticulum stress in tauopathies: contrasting human brain pathology with cellular and animal models

…, MS Marcora, LF Belfiori-Carrasco… - Journal of …, 2019 - content.iospress.com
The accumulation and spreading of protein tau in the human brain are major features of
neurodegenerative disorders known as tauopathies. In addition to several subcellular …

Amyloid-β42 clearance and neuroprotection mediated by X-box binding protein 1 signaling decline with aging in the Drosophila brain

MS Marcora, LF Belfiori-Carrasco, NI Bocai… - Neurobiology of …, 2017 - Elsevier
The unfolded protein response (UPR) may be pathogenically related to Alzheimer's disease.
Yet, the effects of chronic amyloid-β42 (Aβ42) accumulation and UPR activation upon …

[HTML][HTML] Nigral transcriptomic profiles in Engrailed-1 hemizygous mouse models of Parkinson's disease reveal upregulation of oxidative phosphorylation-related …

LF Belfiori, A Dueñas Rey, DM Ralbovszki… - Frontiers in Aging …, 2024 - frontiersin.org
Introduction Parkinson’s disease (PD) is the second most common neurodegenerative
disorder, increasing both in terms of prevalence and incidence. To date, only symptomatic …

[HTML][HTML] A Novel Genetic Screen Identifies Modifiers of Age-Dependent Amyloid β Toxicity in the Drosophila Brain

LF Belfiori-Carrasco, MS Marcora, NI Bocai… - Frontiers in aging …, 2017 - frontiersin.org
The accumulation of amyloid β peptide (Aβ) in the brain of Alzheimer’s disease (AD)
patients begins many years before clinical onset. Such process has been proposed to be …

MHC class II transactivator effects on local and systemic immune responses in an α-synuclein seeded rat model for Parkinson's disease

F Fredlund, I Jimenez-Ferrer, K Grabert, L Belfiori… - bioRxiv, 2022 - biorxiv.org
BACKGROUND Parkinson’s disease (PD) is characterized by alpha-synuclein (α-Syn)
pathology, neurodegeneration and neuroinflammation. HLA variants associated with PD and α-…

The MHC class II transactivator affects local and systemic immune responses in an α-synuclein seeded rat model for Parkinson's disease

F Bäckström, I Jimenez-Ferrer, K Grabert, L Belfiori… - 2023 - researchsquare.com
Parkinson’s disease (PD) is characterized by intraneuronal inclusions of alpha-synuclein (α-Syn),
neurodegeneration and a strong neuroinflammatory component. Studies have shown …

[HTML][HTML] Inhibition of glutamate release, but not of glutamine recycling to glutamate, is involved in delaying the onset of initial lithium-pilocarpine-induced seizures in …

MJ Pawlik, BI Aldana, LF Belfiori-Carrasco… - International Journal of …, 2021 - mdpi.com
Initial seizures observed in young rats during the 60 min after administration of pilocarpine (Pilo)
were delayed and attenuated by pretreatment with a non-convulsive dose of methionine …

Mechanistic Insight into the Attenuation of Initial Pilocarpine-Induced Seizures in Young Rats by a Non-Convulsive MSO Dose

MJ Pawlik, BI Aldana, LF Belfiori-Carrasco… - 2021 - preprints.org
Pretreatment with non-convulsive dose of methionine sulfoximine (MSO) attenuated lithi-um-pilocarpine-induced
(Li-Pilo) seizures in young rats [1]. We hypothesized that the effect of …

[PDF][PDF] HUMAN AND ANIMAL MODELS FOR TRANSLATIONAL RESEARCH ON NEURODEGENERATION: CHALLENGES AND OPPORTUNITIES FROM SOUTH …

A Ibáñez, L Sedeño, AM García, RMJ Deacon… - 2007 - academia.edu
Population aging is among the most important global transformations. Today, 12% of the
world population is of age 60 and over and by the middle of this century this segment will …

Estudio de la neurotoxicidad de péptidos amiloides y proteína tau asociados a demencias humanas en el sistema nervioso de Drosophila

NI Bocai - 2019 - ridaa.unq.edu.ar
La Enfermedad de Alzheimer (EA) esporádica es el principal tipo de demencia en la población
adulta y sus causas aún no se conocen. En cambio, la Demencia Familiar Danesa (DFD…