Histone post-translational modifications (PTMs) play a critical role in chromatin regulation. It
has been proposed that these PTMs form localized ‘codes’ that are read by specialized …

In nucleosomes, histone N-terminal tails exist in dynamic equilibrium between free/accessible
and collapsed/DNA-bound states. The latter state is expected to impact histone N-termini …

BACKGROUND: Patients with constitutive activation of DNA-sensing pathway through
stimulator of IFN (interferon) genes (STING), such as those with STING-associated vasculopathy …

RATIONALE Children with STING‐Associated Vasculopathy with onset in Infancy (SAVI)
spontaneously developed pulmonary hypertension (PH) among other sequela of inflammation. …

Rationale Patients with constitutive activation of DNA sensing pathway through stimulator of
interferon genes (STING), such as those with STING-Associated Vasculopathy with onset in …

Introduction Pulmonary hypertension (PH) is a progressive disease that leads to right heart
failure and death. Increased sympathetic activity in PH patients is associated with a worse …

… by Michael Macedonia from the University of Central Florida and the ITEA scholarships
given to four students including Elaine Lin, Pearly Pandya, Alex Chen and Laylo Mukhsinova. …

Chromatin, the physiological template of all eukaryotic genetic information, is subject to a
diverse array of posttranslational modifications that largely impinge on histone amino termini, …